HitPredict

Interactor 1: CFTR (P13569)
Cystic fibrosis transmembrane conductance regulator (CFTR) (ATP-binding cassette sub-family C member 7) (Channel conductance-controlling ATPase) (EC 5.6.1.6) (cAMP-dependent chloride channel)
Gene: CFTR

Interactor 2: K1C13 (P13646)
Keratin, type I cytoskeletal 13 (Cytokeratin-13) (CK-13) (Keratin-13) (K13)
Gene: KRT13

Species: Homo sapiens

Source: mint

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.66	0.60	0.633

Property	Details
Experiments	35156780, 31324722
Identification Methods	protein complementation assay, affinity chromatography technology, cross-linking study, ubiquitin reconstruction
Interaction Type	direct interaction, physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005634 - nucleus GO:0005829 - cytosol
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 1480 Hs			1 458
+	Hs
		359298 CFTR_HUMAN (1-1480): 0: 1031: 100.00		K1C14_HUMAN (102-416): 3.68e-152: 442: 73.33
+	Hs
		444998 CFTR_HUMAN (1-1480): 0: 1031: 100.00		K1C16_HUMAN (100-429): 1.27e-150: 438: 70.91
+	Hs
		529011 CFTR_HUMAN (1-1480): 0: 1031: 100.00		K1C17_HUMAN (98-444): 3.24e-150: 436: 66.86
+	Hs
		444303 CFTR_HUMAN (1-1480): 0: 1031: 100.00		K1C19_HUMAN (63-413): 1.06e-138: 405: 65.24
+	Hs
		528448 CFTR_HUMAN (1-1480): 0: 1031: 100.00		K1C10_HUMAN (99-410): 4.12e-133: 397: 66.88
+	Hs
		529151 CFTR_HUMAN (1-1480): 0: 1031: 100.00		K1H1_HUMAN (95-422): 4.55e-120: 358: 55.93
+	Hs
		280490 CFTR_HUMAN (1-1480): 0: 1031: 100.00		KT33A_HUMAN (95-431): 8.34e-119: 355: 54.60
+	Hs
		529194 CFTR_HUMAN (1-1480): 0: 1031: 100.00		K1C24_HUMAN (99-449): 5.87e-117: 354: 57.47
+	Hs
		529118 CFTR_HUMAN (1-1480): 0: 1031: 100.00		KT33B_HUMAN (95-422): 4.06e-117: 350: 55.02
+	Hs
		280518 CFTR_HUMAN (1-1480): 0: 1031: 100.00		KRT34_HUMAN (95-437): 4.2e-114: 342: 52.91
+	Hs
		529119 CFTR_HUMAN (1-1480): 0: 1031: 100.00		KRT81_HUMAN (18-418): 5.98e-86: 273: 25.84
+	Hs
		528963 CFTR_HUMAN (1-1480): 0: 1031: 100.00		KRT85_HUMAN (1-436): 2.09e-85: 272: 26.54
+	Hs
		213928 CFTR_HUMAN (1-1480): 0: 1031: 100.00		KRT86_HUMAN (18-456): 6.85e-85: 270: 25.44
+	Hs
		318772 CFTR_HUMAN (1-1480): 0: 1031: 100.00		K2C75_HUMAN (2-428): 2.28e-80: 260: 29.19
+	Hs
		529130 CFTR_HUMAN (1-1480): 0: 1031: 100.00		K2C72_HUMAN (1-419): 3.25e-73: 240: 25.85
+	Hs
		380440 CFTR_HUMAN (1-1480): 0: 1031: 100.00		K2C6B_HUMAN (73-435): 7.01e-68: 228: 24.73
+	Hs
		528760 CFTR_HUMAN (1-1480): 0: 1031: 100.00		K2C6C_HUMAN (73-435): 1.1e-67: 227: 24.73
+	Hs
		528450 CFTR_HUMAN (1-1480): 0: 1031: 100.00		K2C5_HUMAN (83-419): 7.96e-67: 226: 27.56
+	Hs
		529332 CFTR_HUMAN (1-1480): 0: 1031: 100.00		K2C74_HUMAN (40-419): 2.54e-67: 225: 26.25
+	Hs
		359458 CFTR_HUMAN (1-1480): 0: 1031: 100.00		K2C6A_HUMAN (99-435): 1.54e-66: 224: 26.33