Protein: K1C15
Keratin, type I cytoskeletal 15 (Cytokeratin-15) (CK-15) (Keratin-15) (K15)

Gene: K1C15, KRT15
Organism: Homo sapiens
Interactions: 182
UniProt ID: P19012

Gene Ontology (top 5):
GO:0005200 - structural constituent of cytoskeleton
GO:0005634 - nucleus
GO:0005829 - cytosol
GO:0005856 - cytoskeleton
GO:0005882 - intermediate filament

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

385236

K2C6A
Keratin, type II cytoskeletal 6A

8

20

High-throughput

0.976

High

407251

K2C6B
Keratin, type II cytoskeletal 6B

5

20

High-throughput

0.933

High

570353

GFAP
Glial fibrillary acidic protein

4

20

High-throughput

0.915

High

618004

K22E
Keratin, type II cytoskeletal 2 epidermal

4

20

High-throughput

0.906

High

437088

K2C8
Keratin, type II cytoskeletal 8

4

20

High-throughput

0.903

High

566330

K2C5
Keratin, type II cytoskeletal 5

4

20

High-throughput

0.903

High

227204

KRT86
Keratin, type II cuticular Hb6

4

20

High-throughput

0.901

High

618046

K2C79
Keratin, type II cytoskeletal 79

4

20

High-throughput

0.901

High

407384

K2C1
Keratin, type II cytoskeletal 1

3

20

High-throughput

0.875

High

618003

K1C20
Keratin, type I cytoskeletal 20

3

20

High-throughput

0.873

High

618037

K2C71
Keratin, type II cytoskeletal 71

3

20

High-throughput

0.871

High

618048

K2C80
Keratin, type II cytoskeletal 80

3

20

High-throughput

0.871

High

618065

K2C73
Keratin, type II cytoskeletal 73

3

20

High-throughput

0.871

High

618031

KRT81
Keratin, type II cuticular Hb1

3

20

High-throughput

0.861

High

436789

K1C18
Keratin, type I cytoskeletal 18

3

20

High-throughput

0.845

High

618063

K2C1B
Keratin, type II cytoskeletal 1b

3

20

High-throughput

0.845

High

341736

K2C75
Keratin, type II cytoskeletal 75

3

20

High-throughput

0.843

High

606074

DESM
Desmin

3

20

High-throughput

0.843

High

618011

K2C6C
Keratin, type II cytoskeletal 6C

2

20

High-throughput

0.817

High

475515

K1C19
Keratin, type I cytoskeletal 19

2

20

High-throughput

0.793

High

618006

PERI
Peripherin

2

20

High-throughput

0.793

High

451120

NFL
Neurofilament light polypeptide

2

20

High-throughput

0.791

High

617997

K2C4
Keratin, type II cytoskeletal 4

2

20

High-throughput

0.789

High

618019

KRT83
Keratin, type II cuticular Hb3

2

20

High-throughput

0.783

High

618020

KRT85
Keratin, type II cuticular Hb5

2

20

High-throughput

0.783

High

618033

K2C72
Keratin, type II cytoskeletal 72

2

20

High-throughput

0.783

High

618060

K2C74
Keratin, type II cytoskeletal 74

2

20

High-throughput

0.783

High

618071

K2C78
Keratin, type II cytoskeletal 78

2

20

High-throughput

0.783

High

618118

KRT82
Keratin, type II cuticular Hb2

2

20

High-throughput

0.783

High

618021

K22O
Keratin, type II cytoskeletal 2 oral

2

20

High-throughput

0.757

High

618122

ABI2
Abl interactor 2

5

20

High-throughput

0.726

High

618127

RCOR3
REST corepressor 3

4

5

High-throughput

0.710

High

618086

PRP31
U4/U6 small nuclear ribonucleoprotein Prp31

4

3

High-throughput

0.709

High

618083

CCHCR
Coiled-coil alpha-helical rod protein 1

4

13

High-throughput

0.705

High

617998

PSB1
Proteasome subunit beta type-1

4

3

High-throughput

0.698

High

618097

TCHP
Trichoplein keratin filament-binding protein

3

20

High-throughput

0.676

High

169431

HGS
Hepatocyte growth factor-regulated tyrosine kinase substrate

3

15

High-throughput

0.675

High

618005

TXLNA
Alpha-taxilin

3

20

High-throughput

0.675

High

618013

ARFP2
Arfaptin-2

3

5

High-throughput

0.675

High

618049

PPR18
Phostensin

3

8

High-throughput

0.675

High

618096

F110A
Protein FAM110A

3

3

High-throughput

0.675

High

618101

KIFC3
Kinesin-like protein KIFC3

3

14

High-throughput

0.675

High

618098

WAC
WW domain-containing adapter protein with coiled-coil

4

0

High-throughput

0.671

High

618040

AMOT
Angiomotin

3

20

High-throughput

0.667

High

618092

SMRD1
SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily D member 1

3

5

High-throughput

0.667

High

618015

PRS8
26S proteasome regulatory subunit 8

3

5

High-throughput

0.666

High

116852

I6L9F6
NEFL protein

1

20

High-throughput

0.665

High

618026

Q0IIN1
Keratin 77

1

20

High-throughput

0.665

High

618091

SGF29
SAGA-associated factor 29

5

5

High-throughput

0.660

High

292332

RA51D
DNA repair protein RAD51 homolog 4

3

0

High-throughput

0.654

High

618061

KANL1
KAT8 regulatory NSL complex subunit 1

3

0

High-throughput

0.648

High

618001

PSA1
Proteasome subunit alpha type-1

2

3

High-throughput

0.646

High

618075

ZGPAT
Zinc finger CCCH-type with G patch domain-containing protein

2

4

High-throughput

0.646

High

618133

AMOL2
Angiomotin-like protein 2

2

20

High-throughput

0.646

High

618081

LNX1
E3 ubiquitin-protein ligase LNX

4

9

High-throughput

0.632

High

136287

P85B
Phosphatidylinositol 3-kinase regulatory subunit beta

2

20

High-throughput

0.631

High

217054

MS18B
Protein Mis18-beta

2

8

High-throughput

0.628

High

551535

K2C3
Keratin, type II cytoskeletal 3

1

20

High-throughput

0.621

High

474466

VIME
Vimentin

1

20

High-throughput

0.618

High

475743

K2C7
Keratin, type II cytoskeletal 7

1

20

High-throughput

0.618

High

618117

KRT84
Keratin, type II cuticular Hb4

1

20

High-throughput

0.618

High

364118

MOS
Proto-oncogene serine/threonine-protein kinase mos

3

4

High-throughput

0.616

High

618014

LMO4
LIM domain transcription factor LMO4

3

14

High-throughput

0.616

High

618072

TXLNB
Beta-taxilin

3

20

High-throughput

0.616

High

246427

KDM1A
Lysine-specific histone demethylase 1A

2

8

High-throughput

0.606

High

262361

DTNB
Dystrobrevin beta

2

11

High-throughput

0.606

High

333295

SNAPN
SNARE-associated protein Snapin

2

6

High-throughput

0.606

High

353669

DRC4
Dynein regulatory complex subunit 4

2

4

High-throughput

0.606

High

618024

CDK18
Cyclin-dependent kinase 18

2

5

High-throughput

0.606

High

618070

TBC21
TBC1 domain family member 21

2

3

High-throughput

0.606

High

618099

RAMAC
RNA guanine-N7 methyltransferase activating subunit

2

2

High-throughput

0.606

High

618110

CARD9
Caspase recruitment domain-containing protein 9

2

8

High-throughput

0.606

High

288346

UBP2
Ubiquitin carboxyl-terminal hydrolase 2

2

18

High-throughput

0.600

High

618044

SKT
Sickle tail protein homolog

2

2

High-throughput

0.590

High

618079

CA216
UPF0500 protein C1orf216

2

7

High-throughput

0.590

High

343734

LDOC1
Protein LDOC1

2

0

High-throughput

0.582

High

618093

CC120
Coiled-coil domain-containing protein 120

2

3

High-throughput

0.577

High

618114

NOD2
Nucleotide-binding oligomerization domain-containing protein 2

1

12

Small-scale

0.573

High

618062

NUP54
Nucleoporin p54

2

2

High-throughput

0.573

High

352070

MBD3
Methyl-CpG-binding domain protein 3

1

4

High-throughput

0.573

High

617999

CCNC
Cyclin-C

1

6

High-throughput

0.573

High

618002

RBTN2
Rhombotin-2

1

14

High-throughput

0.573

High

618022

CREB5
Cyclic AMP-responsive element-binding protein 5

1

4

High-throughput

0.573

High

618025

TLE5
TLE family member 5

1

3

High-throughput

0.573

High

618036

PKN1
Serine/threonine-protein kinase N1

1

11

High-throughput

0.573

High

618052

MORN3
MORN repeat-containing protein 3

1

3

High-throughput

0.573

High

618064

CEP57
Centrosomal protein of 57 kDa

1

7

High-throughput

0.573

High

618066

GLCTK
Glycerate kinase

1

3

High-throughput

0.573

High

618080

ZN417
Zinc finger protein 417

1

4

High-throughput

0.573

High

618089

SMCE1
SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily E member 1

1

8

High-throughput

0.573

High

618090

HAUS1
HAUS augmin-like complex subunit 1

1

3

High-throughput

0.573

High

618104

BEX2
Protein BEX2

1

9

High-throughput

0.573

High

618113

ZN576
Zinc finger protein 576

1

4

High-throughput

0.573

High

618123

SPG21
Maspardin

1

2

High-throughput

0.573

High

618124

HM20B
SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily E member 1-related

1

9

High-throughput

0.573

High

618132

ADIP
Afadin- and alpha-actinin-binding protein

1

2

High-throughput

0.573

High

618077

CC185
Coiled-coil domain-containing protein 185

2

8

High-throughput

0.555

High

618045

TTC23
Tetratricopeptide repeat protein 23

2

14

High-throughput

0.553

High

618067

Q8IVT4
Hypothetical MGC50722

2

3

High-throughput

0.553

High

618078

TRIMM
Probable E3 ubiquitin-protein ligase TRIML2

2

10

High-throughput

0.553

High

618107

HPLN2
Hyaluronan and proteoglycan link protein 2

2

7

High-throughput

0.553

High

618108

ENKD1
Enkurin domain-containing protein 1

2

3

High-throughput

0.553

High

618129

RSP14
Radial spoke head 14 homolog

2

6

High-throughput

0.553

High

618010

ATPO
ATP synthase peripheral stalk subunit OSCP, mitochondrial

1

0

High-throughput

0.549

High

618111

EPC1
Enhancer of polycomb homolog 1

1

0

High-throughput

0.549

High

618094

A26L1
Putative ankyrin repeat domain-containing protein 26-like 1

2

2

High-throughput

0.544

High

352748

F107A
Actin-associated protein FAM107A

1

2

High-throughput

0.541

High

604990

HXB6
Homeobox protein Hox-B6

1

10

High-throughput

0.541

High

618000

APC
Adenomatous polyposis coli protein

1

6

High-throughput

0.541

High

618029

SNF5
SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily B member 1

1

4

High-throughput

0.541

High

618032

ZN638
Zinc finger protein 638

1

4

High-throughput

0.541

High

618035

PCM1
Pericentriolar material 1 protein

1

7

High-throughput

0.541

High

618069

EXOC8
Exocyst complex component 8

1

4

High-throughput

0.541

High

618082

RHPN1
Rhophilin-1

1

8

High-throughput

0.541

High

618084

TEKT4
Tektin-4

1

6

High-throughput

0.541

High

618095

TS101
Tumor susceptibility gene 101 protein

1

5

High-throughput

0.541

High

618105

DGC6L
Protein DGCR6L

1

2

High-throughput

0.541

High

618112

RIBC2
RIB43A-like with coiled-coils protein 2

1

3

High-throughput

0.541

High

618125

CACO1
Calcium-binding and coiled-coil domain-containing protein 1

1

7

High-throughput

0.541

High

618007

KI67
Proliferation marker protein Ki-67

1

2

High-throughput

0.536

High

618088

TANK
TRAF family member-associated NF-kappa-B activator

1

2

High-throughput

0.536

High

528419

COX5B
Cytochrome c oxidase subunit 5B, mitochondrial

1

3

High-throughput

0.523

High

618023

DEUP1
Deuterosome assembly protein 1

1

11

High-throughput

0.523

High

618042

CTSRT
Cation channel sperm-associated targeting subunit tau

1

2

High-throughput

0.523

High

618043

EFHC1
EF-hand domain-containing protein 1

1

1

High-throughput

0.523

High

618047

ZFY26
Zinc finger FYVE domain-containing protein 26

1

20

High-throughput

0.523

High

618051

KLC3
Kinesin light chain 3

1

12

High-throughput

0.523

High

618068

TRI42
Tripartite motif-containing protein 42

1

20

High-throughput

0.523

High

618073

RIBC1
RIB43A-like with coiled-coils protein 1

1

3

High-throughput

0.523

High

618119

KLC4
Kinesin light chain 4

1

12

High-throughput

0.523

High

618034

MD2BP
MAD2L1-binding protein

1

0

High-throughput

0.518

High

618055

NUD18
8-oxo-dGDP phosphatase NUDT18

1

0

High-throughput

0.518

High

618058

MCM10
Protein MCM10 homolog

1

0

High-throughput

0.518

High

618059

ARC
Activity-regulated cytoskeleton-associated protein

1

0

High-throughput

0.518

High

618106

NIF3L
NIF3-like protein 1

1

0

High-throughput

0.518

High

618027

Q0P5Q0
Thymosin beta-4

1

5

High-throughput

0.515

High

159144

ABLM1
Actin-binding LIM protein 1

1

1

High-throughput

0.494

High

618053

TXD11
Thioredoxin domain-containing protein 11

1

1

High-throughput

0.494

High

618076

USBP1
Harmonin-binding protein USHBP1

1

16

High-throughput

0.494

High

618120

DEPP1
Protein DEPP1

1

1

High-throughput

0.494

High

618126

ABI3
ABI gene family member 3

1

20

High-throughput

0.494

High

618134

TELO2
Telomere length regulation protein TEL2 homolog

1

0

High-throughput

0.486

High

505690

ZN688
Zinc finger protein 688

1

12

High-throughput

0.481

High

618016

TYB4
Thymosin beta-4

1

5

High-throughput

0.481

High

618018

SHPS1
Tyrosine-protein phosphatase non-receptor type substrate 1

1

9

High-throughput

0.481

High

618128

GCP4
Gamma-tubulin complex component 4

1

3

High-throughput

0.481

High

618130

CYH4
Cytohesin-4

1

5

High-throughput

0.481

High

618131

RNF6
E3 ubiquitin-protein ligase RNF6

1

12

High-throughput

0.481

High

240709

PRKN
E3 ubiquitin-protein ligase parkin

1

19

High-throughput

0.479

High

324509

HEXI1
Protein HEXIM1

1

20

High-throughput

0.479

High

484905

ROA1
Heterogeneous nuclear ribonucleoprotein A1

1

14

High-throughput

0.479

High

618008

CRK
Adapter molecule crk

1

20

High-throughput

0.479

High

618009

YAP1
Transcriptional coactivator YAP1

1

20

High-throughput

0.479

High

618017

GRB2
Growth factor receptor-bound protein 2

1

20

High-throughput

0.479

High

618028

TFCP2
Alpha-globin transcription factor CP2

1

8

High-throughput

0.479

High

618030

PKP1
Plakophilin-1

1

8

Small-scale

0.479

High

618039

LARP7
La-related protein 7

1

16

High-throughput

0.479

High

618050

PRP8
Pre-mRNA-processing-splicing factor 8

1

11

High-throughput

0.479

High

618057

MEPCE
7SK snRNA methylphosphate capping enzyme

1

14

High-throughput

0.479

High

618109

RN208
RING finger protein 208

1

19

Small-scale

0.479

High

618116

ANLN
Anillin

1

11

High-throughput

0.479

High

59904

A2BDD9
AMOT protein

1

20

High-throughput

0.470

High

618085

Q8WWE8
CYTH4 protein

1

5

High-throughput

0.470

High

557847

XRCC6
X-ray repair cross-complementing protein 6

1

0

High-throughput

0.458

High

618012

RAB7A
Ras-related protein Rab-7a

1

0

Small-scale

0.458

High

185155

FANCG
Fanconi anemia group G protein

1

1

High-throughput

0.457

High

395463

ESR1
Estrogen receptor

1

15

High-throughput

0.445

High

618074

RYBP
RING1 and YY1-binding protein

1

2

High-throughput

0.445

High

618087

ESR2
Estrogen receptor beta

1

15

High-throughput

0.445

High

293177

CD123
Translation initiation factor eIF2 assembly protein

1

12

High-throughput

0.437

High

618038

MINY4
Probable ubiquitin carboxyl-terminal hydrolase MINDY-4

1

2

Small-scale

0.437

High

3304

A0A0S2Z4G9
Ring finger protein 6 isoform 2

1

7

High-throughput

0.417

High

3526

A0A0S2Z5X4
Zinc finger protein 688 isoform 4

1

11

High-throughput

0.417

High

618103

Q9BVR6
Gamma-tubulin complex component

1

3

High-throughput

0.417

High

618041

ZC21C
Zinc finger C2HC domain-containing protein 1C

4

0

High-throughput

0.368

High

618102

NOC4L
Nucleolar complex protein 4 homolog

2

0

High-throughput

0.337

High

618115

CIP1
E3 ubiquitin-protein ligase CCNB1IP1

2

0

High-throughput

0.327

High

618100

RPP25
Ribonuclease P protein subunit p25

2

0

High-throughput

0.316

High

238696

TIM8A
Mitochondrial import inner membrane translocase subunit Tim8 A

1

0

High-throughput

0.299

High

618056

IKIP
Inhibitor of nuclear factor kappa-B kinase-interacting protein

1

0

High-throughput

0.299

High

618121

CCD87
Coiled-coil domain-containing protein 87

1

0

High-throughput

0.299

High

618054

K0408
Uncharacterized protein KIAA0408

1

0

High-throughput

0.282

High


Service provided by Combinatics, Japan

Last updated: 11Aug2025