HitPredict

Interactor 1: CFTR (P13569)
Cystic fibrosis transmembrane conductance regulator (CFTR) (ATP-binding cassette sub-family C member 7) (Channel conductance-controlling ATPase) (EC 5.6.1.6) (cAMP-dependent chloride channel)
Gene: CFTR

Interactor 2: HNRH3 (P31942)
Heterogeneous nuclear ribonucleoprotein H3 (hnRNP H3) (Heterogeneous nuclear ribonucleoprotein 2H9) (hnRNP 2H9)
Gene: HNRNPH3

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.33	0.60	0.445

Property	Details
Experiments	31324722
Identification Methods	cross-linking study
Interaction Type	association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005634 - nucleus
Homologous interactions	10

Homologous interactions

Color coding for hit scores

	1 1480 Hs			1 346
+	Hs
		529709 CFTR_HUMAN (1-1480): 0: 1031: 100.00		PABP3_HUMAN (8-287): 2.27e-46: 168: 11.89
+	Hs
		528516 CFTR_HUMAN (1-1480): 0: 1031: 100.00		NUCL_HUMAN (5-254): 2.01e-21: 97.3: 17.11
+	Hs
		528841 CFTR_HUMAN (1-1480): 0: 1031: 100.00		HNRH2_HUMAN (9-136): 3.82e-13: 71.9: 28.46
+	Hs
		528638 CFTR_HUMAN (1-1480): 0: 1031: 100.00		HNRH1_HUMAN (9-136): 7.11e-13: 71.1: 27.69
+	Hs
		528812 CFTR_HUMAN (1-1480): 0: 1031: 100.00		HNRPF_HUMAN (9-197): 5.95e-12: 68: 20.40
+	Hs
		529208 CFTR_HUMAN (1-1480): 0: 1031: 100.00		PAP1L_HUMAN (187-276): 6.28e-11: 65.3: 22.58
+	Hs
		516343 CFTR_HUMAN (1-1480): 0: 1031: 100.00		PABP1_HUMAN (187-276): 1.9e-10: 64.2: 18.28
+	Hs
		529069 CFTR_HUMAN (1-1480): 0: 1031: 100.00		PABP4_HUMAN (189-276): 1.96e-10: 63.8: 17.58
+	Sc
		376791 YCFI_YEAST (748-1433): 4.8e-56: 216: 14.59		PABP_YEAST (6-286): 3.77e-45: 164: 12.54
+	Hs
		582437 MRP9_HUMAN (129-648): 1.25e-56: 218: 14.61		NUCL_HUMAN (5-254): 2.01e-21: 97.3: 17.11