HitPredict

Interactor 1: CFTR (P13569)
Cystic fibrosis transmembrane conductance regulator (CFTR) (ATP-binding cassette sub-family C member 7) (Channel conductance-controlling ATPase) (EC 5.6.1.6) (cAMP-dependent chloride channel)
Gene: CFTR

Interactor 2: ARL1 (P40616)
ADP-ribosylation factor-like protein 1
Gene: ARL1

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.60	0.60	0.601

Property	Details
Experiments	26618866, 29924966
Identification Methods	affinity chromatography technology, pull down, anti bait coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005737 - cytoplasm GO:0005829 - cytosol
Homologous interactions	5

Homologous interactions

Color coding for hit scores

	1 1480 Hs			1 181
+	Hs
		528906 CFTR_HUMAN (1-1480): 0: 1031: 100.00		ARF6_HUMAN (5-179): 4.77e-71: 214: 54.29
+	Hs
		528506 CFTR_HUMAN (1-1480): 0: 1031: 100.00		ARF4_HUMAN (1-180): 4.85e-68: 206: 58.33
+	Hs
		528970 CFTR_HUMAN (1-1480): 0: 1031: 100.00		ARF5_HUMAN (1-180): 6.4e-67: 203: 58.33
+	Hs
		706698 MRP1_HUMAN (810-1471): 5.31e-60: 229: 15.70		ARF6_HUMAN (5-179): 4.77e-71: 214: 54.29
+	Hs
		179404 MRP5_HUMAN (774-1479): 5.77e-53: 207: 13.26		ARF6_HUMAN (5-179): 4.77e-71: 214: 54.29