Protein: RISC
Retinoid-inducible serine carboxypeptidase (EC 3.4.16.-) (Serine carboxypeptidase 1)

Gene: RISC, SCPEP1
Organism: Homo sapiens
Interactions: 47
UniProt ID: Q9HB40

Gene Ontology (top 5):
GO:0004185 - serine-type carboxypeptidase activity
GO:0006508 - proteolysis
GO:0042573 - retinoic acid metabolic process
GO:0045776 - negative regulation of blood pressure
GO:0070062 - extracellular exosome

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

699144

CALX
Calnexin

2

4

High-throughput

0.628

High

1280974

CTU1
Cytoplasmic tRNA 2-thiolation protein 1

2

1

High-throughput

0.549

High

488867

FURIN
Furin

1

1

High-throughput

0.536

High

548612

MPRI
Cation-independent mannose-6-phosphate receptor

1

2

High-throughput

0.536

High

1432116

KLK15
Kallikrein-15

1

3

High-throughput

0.536

High

273787

ATS4
A disintegrin and metalloproteinase with thrombospondin motifs 4

1

0

High-throughput

0.513

High

292747

RENR
Renin receptor

1

0

High-throughput

0.513

High

626025

ITIH2
Inter-alpha-trypsin inhibitor heavy chain H2

1

0

High-throughput

0.513

High

1253712

CO039
Uncharacterized protein C15orf39

1

3

High-throughput

0.489

High

1310423

HSC20
Iron-sulfur cluster co-chaperone protein HscB

1

1

High-throughput

0.489

High

1357381

NAT14
Probable N-acetyltransferase 14

1

1

High-throughput

0.489

High

1417683

TX101
Testis-expressed protein 101

1

1

High-throughput

0.489

High

441508

AGAL
Alpha-galactosidase A

1

0

High-throughput

0.458

High

218797

TGON2
Trans-Golgi network integral membrane protein 2

1

4

High-throughput

0.437

High

769223

RFA3
Replication protein A 14 kDa subunit

1

1

High-throughput

0.437

High

1364601

BAP1
Ubiquitin carboxyl-terminal hydrolase BAP1

1

1

High-throughput

0.437

High

437799

HEPS
Serine protease hepsin

1

0

High-throughput

0.426

High

170973

CLGN
Calmegin

1

4

High-throughput

0.407

High

1245922

BRID5
BRICHOS domain-containing protein 5

2

0

High-throughput

0.313

High

1325632

GLT16
Polypeptide N-acetylgalactosaminyltransferase 16

2

0

High-throughput

0.313

High

66666

CC85C
Coiled-coil domain-containing protein 85C

1

0

High-throughput

0.279

Low

168454

NCTR3
Natural cytotoxicity triggering receptor 3

1

0

High-throughput

0.279

Low

873868

PCP4
Calmodulin regulator protein PCP4

1

0

High-throughput

0.279

Low

932764

EMP3
Epithelial membrane protein 3

1

0

High-throughput

0.279

Low

975566

SELT
Thioredoxin reductase-like selenoprotein T

1

0

High-throughput

0.279

Low

1128685

ZN460
Zinc finger protein 460

1

0

High-throughput

0.279

Low

1180698

CTU2
Cytoplasmic tRNA 2-thiolation protein 2

1

0

High-throughput

0.279

Low

1228654

NR3L1
Natural cytotoxicity triggering receptor 3 ligand 1

1

0

High-throughput

0.279

Low

1339794

CADM4
Cell adhesion molecule 4

1

0

High-throughput

0.279

Low

1369491

TANK
TRAF family member-associated NF-kappa-B activator

1

0

High-throughput

0.279

Low

1394267

GMCL1
Germ cell-less protein-like 1

1

0

High-throughput

0.279

Low

1411129

SH23A
SH2 domain-containing protein 3A

1

0

High-throughput

0.279

Low

1416797

5NT1A
Cytosolic 5'-nucleotidase 1A

1

0

High-throughput

0.279

Low

1417359

S26A6
Solute carrier family 26 member 6

1

0

High-throughput

0.279

Low

1437927

STAP1
Signal-transducing adaptor protein 1

1

0

High-throughput

0.279

Low

1349885

ZN507
Zinc finger protein 507

1

0

High-throughput

0.269

Low

1437926

FXL17
F-box/LRR-repeat protein 17

1

0

Small-scale

0.251

Low

1107226

BIRC3
Baculoviral IAP repeat-containing protein 3

1

0

High-throughput

0.249

Low

1324180

PLD6
Mitochondrial cardiolipin hydrolase

1

0

High-throughput

0.249

Low

1429493

CLPB
Mitochondrial disaggregase

1

0

High-throughput

0.249

Low

73855

C1T9B
Complement C1q and tumor necrosis factor-related protein 9B

1

0

High-throughput

0.232

Low

976862

LCN6
Epididymal-specific lipocalin-6

1

0

High-throughput

0.232

Low

1295037

TMM25
Transmembrane protein 25

1

0

High-throughput

0.232

Low

1359246

CA054
Uncharacterized protein C1orf54

1

0

High-throughput

0.232

Low

1366248

LPAR1
Lysophosphatidic acid receptor 1

1

0

High-throughput

0.232

Low

1395167

HIPL1
HHIP-like protein 1

1

0

High-throughput

0.232

Low

1437928

ZSC21
Zinc finger and SCAN domain-containing protein 21

1

0

High-throughput

0.232

Low


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Last updated: 11Aug2025