Protein: CPVL
Probable serine carboxypeptidase CPVL (EC 3.4.16.-) (Carboxypeptidase, vitellogenic-like) (Vitellogenic carboxypeptidase-like protein) (VCP-like protein) (hVLP)

Gene: CPVL
Organism: Homo sapiens
Interactions: 183
UniProt ID: Q9H3G5

Gene Ontology (top 5):
GO:0004185 - serine-type carboxypeptidase activity
GO:0006508 - proteolysis
GO:0070062 - extracellular exosome

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

1357374

NAT14
Probable N-acetyltransferase 14

3

1

High-throughput

0.609

High

867415

CAPZB
F-actin-capping protein subunit beta

2

0

High-throughput

0.602

High

404411

GCR
Glucocorticoid receptor

3

1

Small-scale

0.585

High

1432585

LATS2
Serine/threonine-protein kinase LATS2

2

1

High-throughput

0.567

High

862455

YAP1
Transcriptional coactivator YAP1

2

3

Small-scale

0.558

High

944740

KLF3
Krueppel-like factor 3

2

5

High-throughput

0.558

High

1253798

QSOX2
Sulfhydryl oxidase 2

2

2

High-throughput

0.558

High

1432604

T22D4
TSC22 domain family protein 4

2

2

High-throughput

0.558

High

138873

STK25
Serine/threonine-protein kinase 25

1

2

High-throughput

0.536

High

699117

CALX
Calnexin

1

4

High-throughput

0.536

High

837255

ACTY
Beta-centractin

1

1

High-throughput

0.536

High

958509

ACTZ
Alpha-centractin

1

1

High-throughput

0.536

High

1137008

SEPT2
Septin-2

1

4

High-throughput

0.536

High

1156416

SEPT7
Septin-7

1

4

High-throughput

0.536

High

1326436

MINK1
Misshapen-like kinase 1

1

4

High-throughput

0.536

High

1432602

TNIK
TRAF2 and NCK-interacting protein kinase

1

5

High-throughput

0.536

High

1432607

STK24
Serine/threonine-protein kinase 24

1

2

High-throughput

0.536

High

242908

PRKN
E3 ubiquitin-protein ligase parkin

2

1

High-throughput

0.533

High

866822

CAZA2
F-actin-capping protein subunit alpha-2

1

0

High-throughput

0.513

High

997507

TBB4B
Tubulin beta-4B chain

1

0

High-throughput

0.513

High

1026221

CLH1
Clathrin heavy chain 1

1

0

High-throughput

0.513

High

1038998

NUCB1
Nucleobindin-1

1

0

High-throughput

0.513

High

1110720

DCTN2
Dynactin subunit 2

1

0

High-throughput

0.513

High

1122340

SCRIB
Protein scribble homolog

1

0

High-throughput

0.513

High

162037

MP2K7
Dual specificity mitogen-activated protein kinase kinase 7

1

3

High-throughput

0.489

High

287728

KS6A5
Ribosomal protein S6 kinase alpha-5

1

1

High-throughput

0.489

High

578544

BRAF
Serine/threonine-protein kinase B-raf

1

2

High-throughput

0.489

High

773635

COPB2
Coatomer subunit beta'

1

1

High-throughput

0.489

High

776129

SOX5
Transcription factor SOX-5

1

2

High-throughput

0.489

High

1090915

TRAF2
TNF receptor-associated factor 2

1

3

High-throughput

0.489

High

1115610

ASPP2
Apoptosis-stimulating of p53 protein 2

1

1

High-throughput

0.489

High

1239741

PPR18
Phostensin

1

2

High-throughput

0.489

High

1250424

KSR2
Kinase suppressor of Ras 2

1

2

High-throughput

0.489

High

1310401

HSC20
Iron-sulfur cluster co-chaperone protein HscB

1

1

High-throughput

0.489

High

1312500

PHC2
Polyhomeotic-like protein 2

1

3

High-throughput

0.489

High

1350984

BRSK1
Serine/threonine-protein kinase BRSK1

1

1

High-throughput

0.489

High

1355893

GRK7
Rhodopsin kinase GRK7

1

1

High-throughput

0.489

High

1365288

SEPT8
Septin-8

1

4

High-throughput

0.489

High

1388096

ERLEC
Endoplasmic reticulum lectin 1

1

1

High-throughput

0.489

High

1395248

LMBL3
Lethal(3)malignant brain tumor-like protein 3

1

1

High-throughput

0.489

High

1396262

ASPP1
Apoptosis-stimulating of p53 protein 1

1

1

High-throughput

0.489

High

1408475

VRK1
Serine/threonine-protein kinase VRK1

1

1

High-throughput

0.489

High

1413447

DCTN5
Dynactin subunit 5

1

1

High-throughput

0.489

High

1418958

WNK3
Serine/threonine-protein kinase WNK3

1

1

High-throughput

0.489

High

1432582

PAK6
Serine/threonine-protein kinase PAK 6

1

2

High-throughput

0.489

High

1432584

SNRK
SNF-related serine/threonine-protein kinase

1

1

High-throughput

0.489

High

1432587

NRBP2
Nuclear receptor-binding protein 2

1

2

High-throughput

0.489

High

1432588

SEP11
Septin-11

1

4

High-throughput

0.489

High

1432600

SEPT9
Septin-9

1

4

High-throughput

0.489

High

1432605

KLF12
Krueppel-like factor 12

1

4

High-throughput

0.489

High

1432606

SAR1B
Small COPII coat GTPase SAR1B

1

4

High-throughput

0.489

High

1432608

RPKL1
Ribosomal protein S6 kinase-like 1

1

2

High-throughput

0.489

High

548601

MPRI
Cation-independent mannose-6-phosphate receptor

1

2

High-throughput

0.479

High

1114282

CUL3
Cullin-3

1

1

High-throughput

0.479

High

1432583

FBX6
F-box only protein 6

1

1

High-throughput

0.479

High

1432586

CNBP1
Beta-catenin-interacting protein 1

1

1

High-throughput

0.470

High

456275

CATD
Cathepsin D

1

0

High-throughput

0.458

High

981089

H2B1C
Histone H2B type 1-C/E/F/G/I

1

0

High-throughput

0.458

High

998800

H31
Histone H3.1

1

0

High-throughput

0.458

High

1280492

HUWE1
E3 ubiquitin-protein ligase HUWE1

1

0

High-throughput

0.458

High

1384819

OTUL
Ubiquitin thioesterase otulin

1

0

Small-scale

0.458

High

1118682

KLF9
Krueppel-like factor 9

1

4

High-throughput

0.457

High

877720

SL9A3
Sodium/hydrogen exchanger 3

1

1

High-throughput

0.445

High

933476

S12A2
Solute carrier family 12 member 2

1

1

High-throughput

0.445

High

1168618

SC5AC
Sodium-coupled monocarboxylate transporter 2

1

1

High-throughput

0.445

High

1196216

S22A6
Solute carrier family 22 member 6

1

3

High-throughput

0.445

High

143251

NFIB
Nuclear factor 1 B-type

1

3

High-throughput

0.437

High

210115

CRX
Cone-rod homeobox protein

1

1

High-throughput

0.437

High

218764

TGON2
Trans-Golgi network integral membrane protein 2

1

4

High-throughput

0.437

High

222527

PLRG1
Pleiotropic regulator 1

1

1

High-throughput

0.437

High

339855

KLF8
Krueppel-like factor 8

1

4

High-throughput

0.437

High

348198

M4K4
Mitogen-activated protein kinase kinase kinase kinase 4

1

5

High-throughput

0.437

High

474286

NFIC
Nuclear factor 1 C-type

1

3

High-throughput

0.437

High

506536

F200B
Protein FAM200B

1

1

High-throughput

0.437

High

540950

ERG
Transcriptional regulator ERG

1

1

High-throughput

0.437

High

769158

RFA3
Replication protein A 14 kDa subunit

1

1

High-throughput

0.437

High

776249

SOX6
Transcription factor SOX-6

1

2

High-throughput

0.437

High

938504

PAX9
Paired box protein Pax-9

1

1

High-throughput

0.437

High

957514

UBC12
NEDD8-conjugating enzyme Ubc12

1

1

High-throughput

0.437

High

959251

ABCE1
ATP-binding cassette sub-family E member 1

1

1

High-throughput

0.437

High

971072

UBE2H
Ubiquitin-conjugating enzyme E2 H

1

1

High-throughput

0.437

High

1056650

PAX8
Paired box protein Pax-8

1

1

High-throughput

0.437

High

1086909

CDC20
Cell division cycle protein 20 homolog

1

1

High-throughput

0.437

High

1088014

NFIA
Nuclear factor 1 A-type

1

3

High-throughput

0.437

High

1133658

NFIX
Nuclear factor 1 X-type

1

3

High-throughput

0.437

High

1163900

DUS7
Dual specificity protein phosphatase 7

1

1

High-throughput

0.437

High

1251348

DJC14
DnaJ homolog subfamily C member 14

1

2

High-throughput

0.437

High

1255512

TRI67
Tripartite motif-containing protein 67

1

2

High-throughput

0.437

High

1311648

KIBRA
Protein KIBRA

1

2

Small-scale

0.437

High

1336841

TNR6A
Trinucleotide repeat-containing gene 6A protein

1

2

High-throughput

0.437

High

1351161

SP7
Transcription factor Sp7

1

4

High-throughput

0.437

High

1361635

SSH1
Protein phosphatase Slingshot homolog 1

1

1

High-throughput

0.437

High

1364590

BAP1
Ubiquitin carboxyl-terminal hydrolase BAP1

1

1

High-throughput

0.437

High

1364991

TSC1
Hamartin

1

1

High-throughput

0.437

High

1400792

ATAD5
ATPase family AAA domain-containing protein 5

1

1

Small-scale

0.437

High

1401389

CIC
Protein capicua homolog

1

4

High-throughput

0.437

High

1405636

ELF4
ETS-related transcription factor Elf-4

1

1

High-throughput

0.437

High

1408278

PTN18
Tyrosine-protein phosphatase non-receptor type 18

1

1

High-throughput

0.437

High

1416907

KLF16
Krueppel-like factor 16

1

3

High-throughput

0.437

High

1419290

TRI55
Tripartite motif-containing protein 55

1

2

High-throughput

0.437

High

1432578

RNF41
E3 ubiquitin-protein ligase NRDP1

1

2

Small-scale

0.437

High

1432581

WDR76
WD repeat-containing protein 76

1

1

High-throughput

0.437

High

1432597

ZRAN1
Ubiquitin thioesterase ZRANB1

1

1

High-throughput

0.437

High

1432603

FBW1A
F-box/WD repeat-containing protein 1A

1

2

High-throughput

0.437

High

1402902

CK5P2
CDK5 regulatory subunit-associated protein 2

1

0

High-throughput

0.426

High

1094981

TRAF3
TNF receptor-associated factor 3

1

3

High-throughput

0.407

High

1246158

TRAF7
E3 ubiquitin-protein ligase TRAF7

1

1

Small-scale

0.407

High

1251186

ZNT10
Calcium/manganese antiporter SLC30A10

1

2

High-throughput

0.407

High

1308538

SL9A9
Sodium/hydrogen exchanger 9

1

1

High-throughput

0.407

High

360115

NB5R3
NADH-cytochrome b5 reductase 3

3

0

High-throughput

0.347

High

1241163

LTMD1
LETM1 domain-containing protein 1

3

0

High-throughput

0.347

High

1432589

OCAD1
OCIA domain-containing protein 1

3

0

High-throughput

0.342

High

1082569

NEXN
Nexilin

2

0

High-throughput

0.328

High

1324391

ABD12
Lysophosphatidylserine lipase ABHD12

2

0

High-throughput

0.328

High

1200411

TM177
Transmembrane protein 177

2

0

High-throughput

0.318

High

1430252

5NT3A
Cytosolic 5'-nucleotidase 3A

2

0

High-throughput

0.318

High

1215507

CE162
Centrosomal protein of 162 kDa

2

0

High-throughput

0.307

High

213372

ARHG9
Rho guanine nucleotide exchange factor 9

2

0

High-throughput

0.298

High

66521

RASFA
Ras association domain-containing protein 10

1

0

High-throughput

0.279

Low

127727

TR10A
Tumor necrosis factor receptor superfamily member 10A

1

0

High-throughput

0.279

Low

133380

DCTN6
Dynactin subunit 6

1

0

High-throughput

0.279

Low

549349

SRF
Serum response factor

1

0

High-throughput

0.279

Low

658981

PTPRE
Receptor-type tyrosine-protein phosphatase epsilon

1

0

High-throughput

0.279

Low

766120

PCGF2
Polycomb group RING finger protein 2

1

0

High-throughput

0.279

Low

905676

IRAK1
Interleukin-1 receptor-associated kinase 1

1

0

High-throughput

0.279

Low

1013177

SARNP
SAP domain-containing ribonucleoprotein

1

0

High-throughput

0.279

Low

1035022

KPCE
Protein kinase C epsilon type

1

0

High-throughput

0.279

Low

1125299

FAK2
Protein-tyrosine kinase 2-beta

1

0

High-throughput

0.279

Low

1368115

HDAC2
Histone deacetylase 2

1

0

High-throughput

0.279

Low

1389161

INKA1
PAK4-inhibitor INKA1

1

0

High-throughput

0.279

Low

1390264

NRBF2
Nuclear receptor-binding factor 2

1

0

High-throughput

0.279

Low

1396425

PHAR3
Phosphatase and actin regulator 3

1

0

High-throughput

0.279

Low

1402214

TESK2
Dual specificity testis-specific protein kinase 2

1

0

High-throughput

0.279

Low

1406627

HCD2
3-hydroxyacyl-CoA dehydrogenase type-2

1

0

High-throughput

0.279

Low

1419752

EVG1
UPF0193 protein EVG1

1

0

High-throughput

0.279

Low

1432580

ZMAT4
Zinc finger matrin-type protein 4

1

0

High-throughput

0.279

Low

1432598

AAKG3
5'-AMP-activated protein kinase subunit gamma-3

1

0

High-throughput

0.279

Low

1432599

S18L2
SS18-like protein 2

1

0

High-throughput

0.279

Low

1432601

MD2L2
Mitotic spindle assembly checkpoint protein MAD2B

1

0

High-throughput

0.269

Low

517496

GLI2
Zinc finger protein GLI2

1

0

High-throughput

0.261

Low

225109

TLX3
T-cell leukemia homeobox protein 3

1

0

High-throughput

0.249

Low

286073

SF3B1
Splicing factor 3B subunit 1

1

0

High-throughput

0.249

Low

316008

RECQ4
ATP-dependent DNA helicase Q4

1

0

High-throughput

0.249

Low

363846

EGFR
Epidermal growth factor receptor

1

0

High-throughput

0.249

Low

589666

RFA2
Replication protein A 32 kDa subunit

1

0

High-throughput

0.249

Low

648666

FGFR4
Fibroblast growth factor receptor 4

1

0

High-throughput

0.249

Low

696484

RFA1
Replication protein A 70 kDa DNA-binding subunit

1

0

High-throughput

0.249

Low

808171

CDN1A
Cyclin-dependent kinase inhibitor 1

1

0

High-throughput

0.249

Low

831416

CCNF
Cyclin-F

1

0

High-throughput

0.249

Low

884396

UBE2A
Ubiquitin-conjugating enzyme E2 A

1

0

High-throughput

0.249

Low

900507

FXR2
RNA-binding protein FXR2

1

0

High-throughput

0.249

Low

951420

SC61B
Protein transport protein Sec61 subunit beta

1

0

High-throughput

0.249

Low

991934

DYLT1
Dynein light chain Tctex-type 1

1

0

High-throughput

0.249

Low

1123814

DCTN1
Dynactin subunit 1

1

0

High-throughput

0.249

Low

1135812

HAPR1
HUWE1-associated protein modifying stress responses 1

1

0

High-throughput

0.249

Low

1138052

TNIP1
TNFAIP3-interacting protein 1

1

0

High-throughput

0.249

Low

1210411

MANEA
Glycoprotein endo-alpha-1,2-mannosidase

1

0

High-throughput

0.249

Low

1256589

CE128
Centrosomal protein of 128 kDa

1

0

High-throughput

0.249

Low

1294181

CEP57
Centrosomal protein of 57 kDa

1

0

High-throughput

0.249

Low

1353140

FBF1
Fas-binding factor 1

1

0

High-throughput

0.249

Low

1360884

ASB10
Ankyrin repeat and SOCS box protein 10

1

0

High-throughput

0.249

Low

1382111

F162A
Protein FAM162A

1

0

High-throughput

0.249

Low

1383405

ZUP1
Zinc finger-containing ubiquitin peptidase 1

1

0

Small-scale

0.249

Low

1407240

M3K3
Mitogen-activated protein kinase kinase kinase 3

1

0

High-throughput

0.249

Low

1409710

MICU1
Calcium uptake protein 1, mitochondrial

1

0

High-throughput

0.249

Low

1420879

AMRA1
Activating molecule in BECN1-regulated autophagy protein 1

1

0

High-throughput

0.249

Low

1432579

EGLN3
Prolyl hydroxylase EGLN3

1

0

High-throughput

0.249

Low

1432591

TLS1
Splicing factor C9orf78

1

0

High-throughput

0.249

Low

1432592

WWOX
WW domain-containing oxidoreductase

1

0

High-throughput

0.249

Low

1432594

CNOT2
CCR4-NOT transcription complex subunit 2

1

0

High-throughput

0.249

Low

1432595

TBCD7
TBC1 domain family member 7

1

0

High-throughput

0.249

Low

1432596

LHX3
LIM/homeobox protein Lhx3

1

0

High-throughput

0.249

Low

71179

HPF1L
Putative histone PARylation factor 1-like

1

0

Small-scale

0.232

Low

213244

CP110
Centriolar coiled-coil protein of 110 kDa

1

0

High-throughput

0.232

Low

245004

KATIP
Katanin-interacting protein

1

0

High-throughput

0.232

Low

326868

RIMB1
Peripheral-type benzodiazepine receptor-associated protein 1

1

0

Small-scale

0.232

Low

870453

SC6A9
Sodium- and chloride-dependent glycine transporter 1

1

0

High-throughput

0.232

Low

1227449

A16L1
Autophagy-related protein 16-1

1

0

High-throughput

0.232

Low

1242223

NPAL3
NIPA-like protein 3

1

0

High-throughput

0.232

Low

1332509

POC5
Centrosomal protein POC5

1

0

High-throughput

0.232

Low

1432577

GCP60
Golgi resident protein GCP60

1

0

Small-scale

0.232

Low

1432590

SO1C1
Solute carrier organic anion transporter family member 1C1

1

0

High-throughput

0.232

Low

1432593

GRHL1
Grainyhead-like protein 1 homolog

1

0

High-throughput

0.232

Low


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Last updated: 11Aug2025