HitPredict

Interactor 1: CFTR (P13569)
Cystic fibrosis transmembrane conductance regulator (CFTR) (ATP-binding cassette sub-family C member 7) (Channel conductance-controlling ATPase) (EC 5.6.1.6) (cAMP-dependent chloride channel)
Gene: CFTR

Interactor 2: SERPH (P50454)
Serpin H1 (47 kDa heat shock protein) (Arsenic-transactivated protein 3) (AsTP3) (Cell proliferation-inducing gene 14 protein) (Collagen-binding protein) (Colligin) (Rheumatoid arthritis-related antigen RA-A47)
Gene: SERPINH1

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.68	0.50	0.587

Property	Details
Experiments	26618866, 29924966, 31324722
Identification Methods	affinity chromatography technology, pull down, cross-linking study, anti bait coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	-
Homologous interactions	9

Homologous interactions

Color coding for hit scores

	1 1480 Hs			1 418
+	Hs
		344156 CFTR_HUMAN (1-1480): 0: 1031: 100.00		A1AT_HUMAN (4-410): 4.18e-158: 453: 28.16
+	Hs
		344270 CFTR_HUMAN (1-1480): 0: 1031: 100.00		AACT_HUMAN (10-410): 1.73e-153: 442: 24.15
+	Hs
		344101 CFTR_HUMAN (1-1480): 0: 1031: 100.00		ANT3_HUMAN (10-409): 2.02e-151: 438: 20.76
+	Hs
		528758 CFTR_HUMAN (1-1480): 0: 1031: 100.00		SPB10_HUMAN (42-409): 1.87e-151: 436: 27.27
+	Hs
		528609 CFTR_HUMAN (1-1480): 0: 1031: 100.00		SPB3_HUMAN (41-409): 2.04e-149: 430: 26.79
+	Hs
		397088 CFTR_HUMAN (1-1480): 0: 1031: 100.00		PAI1_HUMAN (13-409): 1.17e-143: 416: 23.76
+	Hs
		529588 CFTR_HUMAN (1-1480): 0: 1031: 100.00		SPB12_HUMAN (42-409): 2.84e-140: 408: 26.73
+	Hs
		179386 MRP5_HUMAN (774-1479): 5.77e-53: 207: 13.26		AACT_HUMAN (10-410): 1.73e-153: 442: 24.15
+	Hs
		839495 ABCA9_HUMAN (75-736): 2.05e-40: 166: 9.96		SPB8_HUMAN (43-409): 1.03e-150: 433: 29.87