Interactor 1: CFTR (P13569)
Cystic fibrosis transmembrane conductance regulator (CFTR) (ATP-binding cassette sub-family C member 7) (Channel conductance-controlling ATPase) (EC 5.6.1.6) (cAMP-dependent chloride channel)
Gene: CFTR

Interactor 2: CLCN3 (P51790)
H(+)/Cl(-) exchange transporter 3 (Chloride channel protein 3) (ClC-3) (Chloride transporter ClC-3)
Gene: CLCN3

Species: Homo sapiens

Source: intact

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.47 0.60 0.536

The method score is based on:

Property Details
Experiments 12471024
Identification Methods pull down
Interaction Type direct interaction, physical association, association

The annotation score is based on:

Property Details
Interacting Pfam domains -
Common GO terms GO:0005254 - chloride channel activity
GO:0005524 - ATP binding
GO:0005765 - lysosomal membrane
GO:0005769 - early endosome
GO:0005886 - plasma membrane
and 7 others

more...

Homologous interactions 1

Homologous interactions

Color coding for hit scores

1 1480
Hs

1 818
+ Hs

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Last updated: 15 Jul 2024