HitPredict

Interactor 1: CFTR (P13569)
Cystic fibrosis transmembrane conductance regulator (CFTR) (ATP-binding cassette sub-family C member 7) (Channel conductance-controlling ATPase) (EC 5.6.1.6) (cAMP-dependent chloride channel)
Gene: CFTR

Interactor 2: ARP2 (P61160)
Actin-related protein 2 (Actin-like protein 2)
Gene: ACTR2

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.68	0.60	0.643

Property	Details
Experiments	31324722, 29924966, 26618866
Identification Methods	affinity chromatography technology, pull down, cross-linking study, anti bait coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005524 - ATP binding GO:0005634 - nucleus GO:0005737 - cytoplasm GO:0005829 - cytosol GO:0016020 - membrane
Homologous interactions	4

Homologous interactions

Color coding for hit scores

	1 1480 Hs			1 394
+	Hs
		528863 CFTR_HUMAN (1-1480): 0: 1031: 100.00		ACTB_HUMAN (1-388): 0: 574: 46.65
+	Hs
		528948 CFTR_HUMAN (1-1480): 0: 1031: 100.00		ACTG_HUMAN (3-388): 0: 573: 46.37
+	Hs
		528949 CFTR_HUMAN (1-1480): 0: 1031: 100.00		ACTH_HUMAN (1-388): 0: 569: 45.62
+	Hs
		528913 CFTR_HUMAN (1-1480): 0: 1031: 100.00		ACTA_HUMAN (3-388): 0: 567: 45.86