HitPredict

Interactor 1: CFTR (P13569)
Cystic fibrosis transmembrane conductance regulator (CFTR) (ATP-binding cassette sub-family C member 7) (Channel conductance-controlling ATPase) (EC 5.6.1.6) (cAMP-dependent chloride channel)
Gene: CFTR

Interactor 2: GBB2 (P62879)
Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-2 (G protein subunit beta-2) (Transducin beta chain 2)
Gene: GNB2

Species: Homo sapiens

Source: mint

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.74	0.60	0.666

Property	Details
Experiments	35156780, 31324722, 29924966
Identification Methods	protein complementation assay, affinity chromatography technology, pull down, cross-linking study, ubiquitin reconstruction
Interaction Type	direct interaction, physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005737 - cytoplasm GO:0005765 - lysosomal membrane GO:0005829 - cytosol GO:0005886 - plasma membrane GO:0016020 - membrane
Homologous interactions	4

Homologous interactions

Color coding for hit scores

	1 1480 Hs			1 340
+	Hs
		529739 CFTR_HUMAN (1-1480): 0: 1031: 100.00		GBB4_HUMAN (1-340): 3.14e-110: 326: 90.00
+	Hs
		528925 CFTR_HUMAN (1-1480): 0: 1031: 100.00		GBB1_HUMAN (1-340): 1.35e-106: 316: 90.29
+	Hs
		529361 CFTR_HUMAN (1-1480): 0: 1031: 100.00		WDR5B_HUMAN (89-340): 4.94e-82: 253: 25.39
+	Hs
		706697 MRP1_HUMAN (810-1471): 5.31e-60: 229: 15.70		WDR5_HUMAN (263-340): 9.69e-19: 87.4: 26.92