HitPredict

Interactor 1: CFTR (P13569)
Cystic fibrosis transmembrane conductance regulator (CFTR) (ATP-binding cassette sub-family C member 7) (Channel conductance-controlling ATPase) (EC 5.6.1.6) (cAMP-dependent chloride channel)
Gene: CFTR

Interactor 2: KRT81 (Q14533)
Keratin, type II cuticular Hb1 (Hair keratin K2.9) (Keratin, hair, basic, 1) (Keratin-81) (K81) (Metastatic lymph node 137 gene protein) (MLN 137) (Type II hair keratin Hb1) (Type-II keratin Kb21) (ghHKb1) (ghHb1)
Gene: KRT81

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.60	0.479

Property	Details
Experiments	31324722
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005829 - cytosol
Homologous interactions	16

Homologous interactions

Color coding for hit scores

	1 1480 Hs			1 505
+	Hs
		61951 CFTR_HUMAN (1-1480): 0: 1031: 100.00		KR87P_HUMAN (169-398): 8.42e-141: 407: 94.78
+	Hs
		380546 CFTR_HUMAN (1-1480): 0: 1031: 100.00		K2C1_HUMAN (70-431): 2.08e-127: 387: 54.67
+	Hs
		408988 CFTR_HUMAN (1-1480): 0: 1031: 100.00		K2C8_HUMAN (25-433): 1.57e-112: 343: 52.81
+	Hs
		213928 CFTR_HUMAN (1-1480): 0: 1031: 100.00		KRT86_HUMAN (1-505): 4.58e-105: 324: 88.32
+	Hs
		529780 CFTR_HUMAN (1-1480): 0: 1031: 100.00		KRT84_HUMAN (1-502): 8.38e-100: 314: 55.03
+	Hs
		528963 CFTR_HUMAN (1-1480): 0: 1031: 100.00		KRT85_HUMAN (1-477): 3.92e-95: 299: 79.51
+	Mm
		514315 CFTR_MOUSE (1-1468): 0: 957: 78.29		K2C8_MOUSE (78-431): 6.95e-114: 347: 57.35
+	Hs
		318772 CFTR_HUMAN (1-1480): 0: 1031: 100.00		K2C75_HUMAN (8-499): 6.34e-82: 266: 43.72
+	Hs
		444525 CFTR_HUMAN (1-1480): 0: 1031: 100.00		K2C7_HUMAN (20-482): 6.73e-78: 253: 47.74
+	Hs
		529130 CFTR_HUMAN (1-1480): 0: 1031: 100.00		K2C72_HUMAN (16-490): 6.27e-75: 247: 43.19
+	Hs
		380440 CFTR_HUMAN (1-1480): 0: 1031: 100.00		K2C6B_HUMAN (73-420): 2.91e-72: 241: 58.29
+	Hs
		528450 CFTR_HUMAN (1-1480): 0: 1031: 100.00		K2C5_HUMAN (73-420): 1.75e-71: 240: 59.43
+	Hs
		528760 CFTR_HUMAN (1-1480): 0: 1031: 100.00		K2C6C_HUMAN (73-420): 5.41e-72: 240: 58.29
+	Hs
		359458 CFTR_HUMAN (1-1480): 0: 1031: 100.00		K2C6A_HUMAN (73-420): 5.87e-71: 237: 58.57
+	Hs
		529332 CFTR_HUMAN (1-1480): 0: 1031: 100.00		K2C74_HUMAN (43-493): 2.15e-70: 235: 43.49
+	Hs
		529503 CFTR_HUMAN (1-1480): 0: 1031: 100.00		KRT35_HUMAN (1-417): 9.84e-66: 221: 26.56