HitPredict

Interactor 1: CFTR (P13569)
Cystic fibrosis transmembrane conductance regulator (CFTR) (ATP-binding cassette sub-family C member 7) (Channel conductance-controlling ATPase) (EC 5.6.1.6) (cAMP-dependent chloride channel)
Gene: CFTR

Interactor 2: CNN2 (Q99439)
Calponin-2 (Calponin H2, smooth muscle) (Neutral calponin)
Gene: CNN2

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.62	0.60	0.611

Property	Details
Experiments	26618866, 31324722
Identification Methods	affinity chromatography technology, anti bait coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0016020 - membrane GO:0051649 - establishment of localization in cell
Homologous interactions	7

Homologous interactions

Color coding for hit scores

	1 1480 Hs			1 309
+	Hs
		529160 CFTR_HUMAN (1-1480): 0: 1031: 100.00		CNN3_HUMAN (4-306): 3.73e-147: 418: 65.48
+	Hs
		528692 CFTR_HUMAN (1-1480): 0: 1031: 100.00		TAGL2_HUMAN (7-190): 6.41e-72: 222: 42.35
+	Hs
		528992 CFTR_HUMAN (1-1480): 0: 1031: 100.00		TAGL_HUMAN (7-192): 4.25e-71: 220: 37.19
+	Hs
		529357 CFTR_HUMAN (1-1480): 0: 1031: 100.00		IQGA3_HUMAN (4-138): 5.27e-39: 148: 16.33
+	Hs
		528745 CFTR_HUMAN (1-1480): 0: 1031: 100.00		IQGA1_HUMAN (7-138): 1.55e-37: 144: 18.75
+	Hs
		529919 CFTR_HUMAN (1-1480): 0: 1031: 100.00		LIMC1_HUMAN (32-157): 2.61e-33: 131: 30.99
+	Hs
		529483 CFTR_HUMAN (1-1480): 0: 1031: 100.00		LMO7_HUMAN (38-149): 4.47e-32: 127: 29.60