Interactor 1: AT1A3 (P13637)
Sodium/potassium-transporting ATPase subunit alpha-3 (Na(+)/K(+) ATPase alpha-3 subunit) (EC 7.2.2.13) (Na(+)/K(+) ATPase alpha(III) subunit) (Sodium pump subunit alpha-3)
Gene: ATP1A3

Interactor 2: ATP4A (P20648)
Potassium-transporting ATPase alpha chain 1 (EC 7.2.2.19) (Gastric H(+)/K(+) ATPase subunit alpha) (Proton pump)
Gene: ATP4A

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score Annotation score Interaction score
0.47 1.00 0.691

The method score is based on:

Property Details
Experiments 33961781
Identification Methods affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type physical association, association

The annotation score is based on:

Property Details
Interacting Pfam domains Cation_ATPase~E1-E2_ATPase, Cation_ATPase_C~Cation_ATPase_C, Cation_ATPase_C~E1-E2_ATPase, Cation_ATPase_C~Hydrolase, Cation_ATPase_N~E1-E2_ATPase, Cation_ATPase_N~Hydrolase, E1-E2_ATPase~E1-E2_ATPase, E1-E2_ATPase~Hydrolase
Common GO terms GO:0005391 - P-type sodium:potassium-exchanging transporter activity
GO:0005524 - ATP binding
GO:0005886 - plasma membrane
GO:0006883 - intracellular sodium ion homeostasis
GO:0016887 - ATP hydrolysis activity
and 4 others

more...

Homologous interactions 12

Homologous interactions

Color coding for hit scores

1 1013
Hs

1 1035
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Last updated: 15 Jul 2024