HitPredict

Interactor 1: RL4A (P10664)
Large ribosomal subunit protein uL4A (60S ribosomal protein L4-A) (L2) (RP2) (YL2)
Gene: RPL4A

Interactor 2: SPB4 (P25808)
ATP-dependent rRNA helicase SPB4 (EC 3.6.4.13) (Suppressor of PAB1 protein 4)
Gene: SPB4

Species: Saccharomyces cerevisiae S288C

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.56	0.60	0.584

Property	Details
Experiments	37811893, 21825077
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0003723 - RNA binding
Homologous interactions	9

Homologous interactions

Color coding for hit scores

	1 362 Sc			1 606
+	Hs
		785482 RL4_HUMAN (2-339): 3.61e-177: 500: 59.29		DDX18_HUMAN (6-467): 5.11e-159: 472: 29.61
+	Sc
		682335 RL4B_YEAST (1-362): 0: 515: 99.72		SPB4_YEAST (1-606): 7.37e-148: 442: 100.00
+	Sc
		531867 RL4A_YEAST (1-362): 0: 515: 100.00		HAS1_YEAST (6-467): 2.43e-138: 414: 30.98
+	Sc
		885073 RL4B_YEAST (1-362): 0: 515: 99.72		HAS1_YEAST (6-467): 2.43e-138: 414: 30.98
+	Sc
		531611 RL4A_YEAST (1-362): 0: 515: 100.00		DBP2_YEAST (2-402): 2.16e-123: 376: 25.43
+	Hs
		141349 RL4_HUMAN (2-339): 3.61e-177: 500: 59.29		DDX3X_HUMAN (4-406): 1.33e-114: 358: 24.64
+	Sc
		531599 RL4A_YEAST (1-362): 0: 515: 100.00		DBP4_YEAST (21-467): 7.03e-51: 189: 31.36
+	Sc
		632703 RL4B_YEAST (1-362): 0: 515: 99.72		DBP4_YEAST (21-467): 7.03e-51: 189: 31.36
+	Hs
		785134 RL4_HUMAN (2-339): 3.61e-177: 500: 59.29		DDX10_HUMAN (21-472): 5.25e-47: 179: 29.67