HitPredict

Interactor 1: RL4A (P10664)
Large ribosomal subunit protein uL4A (60S ribosomal protein L4-A) (L2) (RP2) (YL2)
Gene: RPL4A

Interactor 2: HAS1 (Q03532)
ATP-dependent RNA helicase HAS1 (EC 3.6.4.13) (Helicase associated with SET1 protein 1)
Gene: HAS1

Species: Saccharomyces cerevisiae S288C

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.56	0.60	0.584

Property	Details
Experiments	30568249, 31511893
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0003723 - RNA binding
Homologous interactions	12

Homologous interactions

Color coding for hit scores

	1 362 Sc			1 505
+	Sc
		531599 RL4A_YEAST (1-362): 0: 515: 100.00		DBP4_YEAST (3-501): 5.54e-165: 487: 37.70
+	Sc
		632703 RL4B_YEAST (1-362): 0: 515: 99.72		DBP4_YEAST (3-501): 5.54e-165: 487: 37.70
+	Sc
		885073 RL4B_YEAST (1-362): 0: 515: 99.72		HAS1_YEAST (1-505): 9.17e-165: 477: 100.00
+	Hs
		785134 RL4_HUMAN (2-339): 3.61e-177: 500: 59.29		DDX10_HUMAN (5-505): 1.99e-148: 448: 37.87
+	Hs
		785482 RL4_HUMAN (2-339): 3.61e-177: 500: 59.29		DDX18_HUMAN (2-492): 2.67e-138: 415: 59.76
+	Sc
		531611 RL4A_YEAST (1-362): 0: 515: 100.00		DBP2_YEAST (5-421): 2.01e-132: 396: 29.22
+	Hs
		141349 RL4_HUMAN (2-339): 3.61e-177: 500: 59.29		DDX3X_HUMAN (4-428): 1.05e-126: 385: 27.77
+	Hs
		785458 RL4_HUMAN (2-339): 3.61e-177: 500: 59.29		DDX31_HUMAN (9-505): 3.74e-82: 274: 32.37
+	Hs
		785359 RL4_HUMAN (2-339): 3.61e-177: 500: 59.29		DDX27_HUMAN (44-441): 6.78e-71: 242: 37.04
+	Sc
		584244 RL4B_YEAST (1-362): 0: 515: 99.72		MS116_YEAST (5-409): 4.71e-64: 221: 35.63
+	Sc
		531626 RL4A_YEAST (1-362): 0: 515: 100.00		SPB4_YEAST (56-488): 1.91e-61: 213: 33.41
+	Sc
		682335 RL4B_YEAST (1-362): 0: 515: 99.72		SPB4_YEAST (56-488): 1.91e-61: 213: 33.41