Interactor 1: CD28 (P10747)
T-cell-specific surface glycoprotein CD28 (TP44) (CD antigen CD28)
Gene: CD28
Interactor 2: CTLA4 (P16410)
Cytotoxic T-lymphocyte protein 4 (Cytotoxic T-lymphocyte-associated antigen 4) (CTLA-4) (CD antigen CD152)
Gene: CTLA4
Species: Homo sapiens
Source: intact
Category: High-throughput
Confidence: High
| Method score | Annotation score | Interaction score |
|---|---|---|
| 0.33 | 1.00 | 0.575 |
The method score is based on:
| Property | Details |
|---|---|
| Experiments | unassigned3799 |
| Identification Methods | anti tag coimmunoprecipitation |
| Interaction Type | association |
The annotation score is based on:
| Property | Details |
|---|---|
| Interacting Pfam domains | V-set~V-set_2 |
| Common GO terms | GO:0005886 - plasma membrane GO:0009897 - external side of plasma membrane GO:0050852 - T cell receptor signaling pathway GO:0098636 - protein complex involved in cell adhesion |
| Homologous interactions | 2 |
Homologous interactions
Color coding for hit scores 
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Service provided by Combinatics, Japan
Last updated: 11Aug2025
