Interactor 1: CEAM1 (P13688)
Carcinoembryonic antigen-related cell adhesion molecule 1 (Biliary glycoprotein 1) (BGP-1) (CD antigen CD66a)
Gene: CEACAM1

Interactor 2: HAVR2 (Q8TDQ0)
Hepatitis A virus cellular receptor 2 (HAVcr-2) (T-cell immunoglobulin and mucin domain-containing protein 3) (TIMD-3) (T-cell immunoglobulin mucin receptor 3) (TIM-3) (T-cell membrane protein 3) (CD antigen CD366)
Gene: HAVCR2

Species: Homo sapiens

Source: intact

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.47 1.00 0.690

The method score is based on:

Property Details
Experiments 25363763
Identification Methods pull down, anti tag coimmunoprecipitation, anti bait coimmunoprecipitation
Interaction Type physical association

The annotation score is based on:

Property Details
Interacting Pfam domains V-set~ig, Ig_2~V-set, Ig_3~V-set, V-set~V-set
Common GO terms GO:0002859 - negative regulation of natural killer cell mediated cytotoxicity directed against tumor cell target
GO:0009986 - cell surface
Homologous interactions 1

Homologous interactions

Color coding for hit scores

1 526
Hs

1 301
+ Mm

Service provided by Combinatics, Japan

Last updated: 15 Jul 2024