Protein: CDK1
Cyclin-dependent kinase 1 (CDK1) (EC 2.7.11.22) (EC 2.7.11.23) (Cell division control protein 2 homolog) (Cell division protein kinase 1) (p34 protein kinase)

Gene: CDK1
Organism: Drosophila melanogaster
Interactions: 58
UniProt ID: P23572

Gene Ontology (top 5):
GO:0000082 - G1/S transition of mitotic cell cycle
GO:0000086 - G2/M transition of mitotic cell cycle
GO:0001700 - embryonic development via the syncytial blastoderm
GO:0004672 - protein kinase activity
GO:0004674 - protein serine/threonine kinase activity

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

632446

CCNB
G2/mitotic-specific cyclin-B

9

20

Small-scale

0.964

High

575836

CCNA
G2/mitotic-specific cyclin-A

8

20

Small-scale

0.956

High

660382

CCNE
G1/S-specific cyclin-E

4

20

Small-scale

0.881

High

660402

CCNB3
G2/mitotic-specific cyclin-B3

3

20

Small-scale

0.839

High

660412

Q9VHN1
Cyclin-dependent kinases regulatory subunit

5

20

Small-scale

0.816

High

660377

CCNC
Cyclin-C

2

20

High-throughput

0.785

High

660383

TWINE
Cdc25-like protein phosphatase twine

2

18

High-throughput

0.785

High

660401

Q961D1
Cyclin-K

2

20

High-throughput

0.785

High

660384

CKS1
Cyclin-dependent kinases regulatory subunit

4

20

Small-scale

0.773

High

660381

WEE1
Wee1-like protein kinase

2

15

Small-scale

0.727

High

660389

GLIS2
Zinc finger protein GLIS2 homolog

1

2

High-throughput

0.656

High

660400

CYCG
Cyclin G

1

20

High-throughput

0.656

High

362463

ABL
Tyrosine-protein kinase Abl

1

13

Small-scale

0.647

High

660410

CRBN
Protein cereblon

1

0

High-throughput

0.622

High

303988

O76513
Cyclin-H

1

20

High-throughput

0.621

High

660394

Q7KUZ5
Cyclin D, isoform D

1

20

High-throughput

0.621

High

660417

Q9VZP3
Cyclin J, isoform A

1

20

Small-scale

0.618

High

195958

O17144
Cyclin-H

1

20

High-throughput

0.590

High

660385

Q24158
Cyclin D

1

20

Small-scale

0.590

High

660391

Q7K306
cyclin-dependent kinase

1

14

High-throughput

0.590

High

660416

Q9VXM1
LD22957p

1

20

High-throughput

0.590

High

660380

RUX
Cell cycle negative regulator roughex

2

0

High-throughput

0.547

High

660414

CH60B
60 kDa heat shock protein homolog 1, mitochondrial

1

12

High-throughput

0.508

High

195730

ORC1
Origin recognition complex subunit 1

1

13

Small-scale

0.501

High

660386

ORC2
Origin recognition complex subunit 2

1

6

Small-scale

0.501

High

660388

E2F1
Transcription factor E2f1

1

14

Small-scale

0.501

High

649193

Z600
Protein Z600

1

0

Small-scale

0.493

High

660411

Q9VHK8
Aaquetzalli, isoform A

1

0

High-throughput

0.486

High

660406

Q9VD04
Uncharacterized protein, isoform B

1

4

High-throughput

0.481

High

380844

H1
Histone H1

1

0

Small-scale

0.480

High

660390

Q7K180
LD02709p

1

0

Small-scale

0.480

High

660378

PSC
Polycomb group protein Psc

1

5

Small-scale

0.479

High

660392

Q7KA43
Anaphase-promoting complex subunit 11

1

1

Small-scale

0.479

High

614865

DHAPP
3,4-dihydroxyphenylacetaldehyde synthase

1

1

High-throughput

0.464

High

660396

Q86BR6
Autophagy-related 16, isoform C

1

6

High-throughput

0.464

High

660398

Q8SYL1
Glutamate-rich WD repeat-containing protein 1

1

3

High-throughput

0.464

High

660404

MFRN
Mitoferrin

1

4

High-throughput

0.464

High

660405

Q9VC60
BUD13 homolog

1

4

High-throughput

0.464

High

660415

Q9VVC8
LD23434p

1

7

High-throughput

0.464

High

304927

CRY1
Cryptochrome-1

1

0

High-throughput

0.458

High

118514

M9NES5
Histone gene-specific epigenetic repressor in late S phase, isoform H

1

5

Small-scale

0.457

High

660407

Q9VD05
RT01151p

1

5

High-throughput

0.457

High

660395

Q7YZ95
S-phase kinase-associated protein 2

1

6

Small-scale

0.437

High

660403

Q9I7L8
Cyclosome subunit 8

1

6

Small-scale

0.437

High

660418

Q9W1E5
Anaphase-promoting complex subunit 2

1

9

Small-scale

0.437

High

660420

Q9W4H9
Fizzy-related protein homolog

1

16

Small-scale

0.437

High

660399

Q94513
Boundary element associated factor

1

0

Small-scale

0.426

High

660379

RL19
Large ribosomal subunit protein eL19

1

2

High-throughput

0.417

High

381691

H3
Histone H3

1

2

High-throughput

0.348

High

660421

Q9Y0S9
Abelson interacting protein, isoform A

1

0

Small-scale

0.288

High

660393

Q7KMG7
DNA excision repair protein ERCC-1

1

0

High-throughput

0.265

Low

660408

Q9VDM7
Trimethyllysine dioxygenase, mitochondrial

1

0

High-throughput

0.265

Low

660409

Q9VEX4
FI24319p1

1

0

High-throughput

0.265

Low

660413

Q9VNV2
GEO05133p1

1

0

High-throughput

0.265

Low

660419

USO1
General vesicular transport factor p115

1

0

Small-scale

0.249

Low

660387

ATP5H
ATP synthase subunit d, mitochondrial

1

0

High-throughput

0.238

Low

660397

Q8IQI9
RE41427p

1

0

High-throughput

0.238

Low

628936

OTE
Otefin

1

0

High-throughput

0.198

Low


Service provided by Combinatics, Japan

Last updated: 11Aug2025