HitPredict

Interactor 1: PRG2 (P13727)
Bone marrow proteoglycan (BMPG) (Proteoglycan 2) [Cleaved into: Eosinophil granule major basic protein (EMBP) (MBP) (Pregnancy-associated major basic protein)]
Gene: PRG2

Interactor 2: RMD5A (Q9H871)
E3 ubiquitin-protein transferase RMND5A (EC 2.3.2.27) (P44CTLH) (Protein RMD5 homolog A)
Gene: RMND5A

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.74	0.50	0.609

Property	Details
Experiments	26186194, 28514442, 33961781
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	-
Homologous interactions	9

Homologous interactions

Color coding for hit scores

	1 222 Hs			1 391
+	Hs
		1333471 PRG3_HUMAN (12-222): 3.37e-54: 174: 49.30		RMD5A_HUMAN (1-391): 2.58e-160: 457: 100.00
+	Hs
		533042 PRG2_HUMAN (1-222): 3.43e-57: 182: 100.00		RMD5B_HUMAN (1-391): 2.2e-152: 437: 69.72
+	Hs
		1291950 PRG3_HUMAN (12-222): 3.37e-54: 174: 49.30		RMD5B_HUMAN (1-391): 2.2e-152: 437: 69.72
+	Hs
		532992 PRG2_HUMAN (1-222): 3.43e-57: 182: 100.00		MAEA_HUMAN (25-390): 1.22e-111: 334: 20.05
+	Hs
		1185168 PRG3_HUMAN (12-222): 3.37e-54: 174: 49.30		MAEA_HUMAN (25-390): 1.22e-111: 334: 20.05
+	Hs
		533083 PRG2_HUMAN (1-222): 3.43e-57: 182: 100.00		GID8_HUMAN (114-280): 5.61e-39: 141: 17.54
+	Hs
		1347497 PRG3_HUMAN (12-222): 3.37e-54: 174: 49.30		GID8_HUMAN (114-280): 5.61e-39: 141: 17.54
+	Hs
		533052 PRG2_HUMAN (1-222): 3.43e-57: 182: 100.00		RANB9_HUMAN (87-214): 3.61e-11: 66.7: 16.41
+	Hs
		1301835 PRG3_HUMAN (12-222): 3.37e-54: 174: 49.30		RANB9_HUMAN (87-214): 3.61e-11: 66.7: 16.41