Protein: HOS2
Probable histone deacetylase HOS2 (EC 3.5.1.98)

Gene: HOS2
Organism: Saccharomyces cerevisiae S288C
Interactions: 45
UniProt ID: P53096

Gene Ontology (top 5):
GO:0004407 - histone deacetylase activity
GO:0005634 - nucleus
GO:0005737 - cytoplasm
GO:0006355 - regulation of DNA-templated transcription
GO:0006974 - DNA damage response

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

672777

SNT1
Probable DNA-binding protein SNT1

4

20

Small-scale

0.887

High

781769

SET3
SET domain-containing protein 3

6

20

Small-scale

0.727

High

796842

SIF2
SIR4-interacting protein SIF2

5

18

Small-scale

0.712

High

575975

CYPH
Peptidyl-prolyl cis-trans isomerase

5

4

Small-scale

0.709

High

917106

H3
Histone H3

1

17

Small-scale

0.690

High

825202

HOS4
Protein HOS4

4

11

Small-scale

0.687

High

577566

CYC8
General transcriptional corepressor CYC8

2

10

Small-scale

0.623

High

893427

ZDS1
Protein ZDS1

2

2

High-throughput

0.621

High

381570

H2B2
Histone H2B.2

1

17

High-throughput

0.575

High

917103

HOS2
Probable histone deacetylase HOS2

1

15

High-throughput

0.575

High

917109

HOS3
Histone deacetylase HOS3

1

17

High-throughput

0.575

High

810731

TCPB
T-complex protein 1 subunit beta

2

20

High-throughput

0.571

High

844419

TCPH
T-complex protein 1 subunit eta

2

20

High-throughput

0.571

High

811124

TCPZ
T-complex protein 1 subunit zeta

2

20

High-throughput

0.521

High

917104

HST1
NAD-dependent protein deacetylase HST1

1

8

Small-scale

0.515

High

704626

SBA1
Co-chaperone protein SBA1

1

1

Small-scale

0.481

High

402059

RPB1
DNA-directed RNA polymerase II subunit RPB1

1

1

Small-scale

0.479

High

707678

TF2B
Transcription initiation factor IIB

1

2

High-throughput

0.479

High

805558

SET1
Histone-lysine N-methyltransferase, H3 lysine-4 specific

1

20

Small-scale

0.479

High

382228

H4
Histone H4

1

12

High-throughput

0.445

High

394743

EF1A
Elongation factor 1-alpha

1

4

High-throughput

0.445

High

453697

PYR1
Multifunctional protein URA2

1

9

High-throughput

0.445

High

527211

HSP72
Heat shock protein SSA2

1

13

High-throughput

0.445

High

545606

SSB1
Ribosome-associated molecular chaperone SSB1

1

14

High-throughput

0.445

High

793179

AKL1
Serine/threonine-protein kinase AKL1

1

6

High-throughput

0.445

High

794197

ISW1
ISWI chromatin-remodeling complex ATPase ISW1

1

20

High-throughput

0.445

High

806318

KOG1
Target of rapamycin complex 1 subunit KOG1

1

15

High-throughput

0.445

High

836797

MPG1
Mannose-1-phosphate guanyltransferase

1

2

High-throughput

0.445

High

865007

TCPQ
T-complex protein 1 subunit theta

1

20

High-throughput

0.445

High

917037

MCM6
DNA replication licensing factor MCM6

1

4

High-throughput

0.445

High

917107

CDC14
Tyrosine-protein phosphatase CDC14

1

2

High-throughput

0.445

High

917110

RUVB1
RuvB-like protein 1

1

3

High-throughput

0.445

High

917111

TOS4
Protein TOS4

1

2

High-throughput

0.445

High

917105

NAF1
H/ACA ribonucleoprotein complex non-core subunit NAF1

1

0

High-throughput

0.438

High

739700

SPT16
FACT complex subunit SPT16

1

1

High-throughput

0.437

High

828301

MKT1
Post-transcriptional regulator MKT1

1

0

High-throughput

0.426

High

917112

YB11B
Transposon Ty1-BL Gag-Pol polyprotein

1

0

High-throughput

0.426

High

554028

TCPA
T-complex protein 1 subunit alpha

1

20

High-throughput

0.407

High

626821

HSP60
Heat shock protein 60, mitochondrial

1

16

High-throughput

0.407

High

810855

TCPG
T-complex protein 1 subunit gamma

1

20

High-throughput

0.407

High

810990

TCPD
T-complex protein 1 subunit delta

1

20

High-throughput

0.407

High

823622

TCPE
T-complex protein 1 subunit epsilon

1

20

High-throughput

0.407

High

864299

NET1
Nucleolar protein NET1

1

1

High-throughput

0.407

High

917108

TOF2
Topoisomerase 1-associated factor 2

1

1

High-throughput

0.407

High


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Last updated: 11Aug2025