HitPredict

Interactor 1: KAP2 (P13861)
cAMP-dependent protein kinase type II-alpha regulatory subunit
Gene: PRKAR2A

Interactor 2: CK5P2 (Q96SN8)
CDK5 regulatory subunit-associated protein 2 (CDK5 activator-binding protein C48) (Centrosome-associated protein 215)
Gene: CDK5RAP2

Species: Homo sapiens

Source: intact

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.66	0.60	0.633

Property	Details
Experiments	29162697, 34079125, 35709258
Identification Methods	affinity chromatography technology, proximity labelling technology, anti bait coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005737 - cytoplasm GO:0005813 - centrosome GO:0005829 - cytosol GO:0070062 - extracellular exosome
Homologous interactions	10

Homologous interactions

Color coding for hit scores

	1 404 Hs			1 1893
+	Hs
		679385 KAP3_HUMAN (4-402): 1.97e-123: 365: 64.34		CK5P2_HUMAN (1-1893): 4.16e-171: 572: 100.00
+	Hs
		533842 KAP2_HUMAN (1-404): 6.63e-138: 401: 100.00		MYOME_HUMAN (50-1479): 6.18e-23: 109: 11.47
+	Mm
		1194535 Q8K1M3_MOUSE (1-404): 1.02e-130: 383: 85.89		MYOME_MOUSE (25-1161): 4.31e-19: 96.9: 10.90
+	Hs
		679355 KAP3_HUMAN (4-402): 1.97e-123: 365: 64.34		MYOME_HUMAN (50-1479): 6.18e-23: 109: 11.47
+	Mm
		519440 KAP2_MOUSE (1-404): 5.82e-127: 373: 85.40		MYOME_MOUSE (25-1161): 4.31e-19: 96.9: 10.90
+	Mm
		679428 KAP3_MOUSE (4-402): 2.28e-121: 359: 65.13		MYOME_MOUSE (25-1161): 4.31e-19: 96.9: 10.90
+	Hs
		498339 KAP0_HUMAN (210-396): 6.96e-18: 86.4: 22.46		CP250_HUMAN (118-1875): 1.86e-61: 236: 9.97
+	Hs
		528402 KAP1_HUMAN (215-396): 4.15e-17: 84: 22.53		MYH8_HUMAN (923-1875): 1.35e-32: 141: 11.98
+	Hs
		498293 KAP0_HUMAN (210-396): 6.96e-18: 86.4: 22.46		MYOME_HUMAN (50-1479): 6.18e-23: 109: 11.47
+	Hs
		522594 KAP1_HUMAN (215-396): 4.15e-17: 84: 22.53		MYH7_HUMAN (36-501): 1e-15: 86.1: 9.77