Protein: IRF5
Interferon regulatory factor 5 (IRF-5)

Gene: IRF5
Organism: Mus musculus
Interactions: 17
UniProt ID: P56477

Gene Ontology (top 5):
GO:0000976 - transcription cis-regulatory region binding
GO:0000981 - DNA-binding transcription factor activity, RNA polymerase II-specific
GO:0001228 - DNA-binding transcription activator activity, RNA polymerase II-specific
GO:0002720 - positive regulation of cytokine production involved in immune response
GO:0005634 - nucleus

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

648037

MYD88
Myeloid differentiation primary response protein MyD88

3

20

Small-scale

0.650

High

660942

IRF8
Interferon regulatory factor 8

1

15

High-throughput

0.618

High

940796

TRAF6
TNF receptor-associated factor 6

2

20

Small-scale

0.584

High

940799

IRAK1
Interleukin-1 receptor-associated kinase 1

2

2

Small-scale

0.584

High

940802

TBK1
Serine/threonine-protein kinase TBK1

1

14

High-throughput

0.501

High

940801

Q8C964
Zinc finger protein 764

1

1

High-throughput

0.481

High

148441

BIRC3
Baculoviral IAP repeat-containing protein 3

1

3

Small-scale

0.479

High

378385

IFNB
Interferon beta

1

20

Small-scale

0.479

High

456562

IFNA4
Interferon alpha-4

1

20

Small-scale

0.479

High

532186

IL1B
Interleukin-1 beta

1

2

Small-scale

0.479

High

849289

IL12B
Interleukin-12 subunit beta

1

8

Small-scale

0.479

High

940797

STING
Stimulator of interferon genes protein

1

2

High-throughput

0.479

High

940800

PELI1
E3 ubiquitin-protein ligase pellino homolog 1

1

1

Small-scale

0.479

High

98286

E9QAP1
Zinc finger protein 764

1

1

High-throughput

0.457

High

940798

NFAC2
Nuclear factor of activated T-cells, cytoplasmic 2

1

20

High-throughput

0.457

High

508994

UBC
Polyubiquitin-C [Cleaved into: Ubiquitin; Ubiquitin-related 1; Ubiquitin-related 2]

1

3

Small-scale

0.437

High

519017

IL7
Interleukin-7

1

2

Small-scale

0.437

High


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Last updated: 11Aug2025