Interactor 1: DNMT1 (P13864)
DNA (cytosine-5)-methyltransferase 1 (Dnmt1) (Met-1) (EC 2.1.1.37) (DNA methyltransferase MmuI) (DNA MTase MmuI) (M.MmuI) (MCMT)
Gene: DNMT1

Interactor 2: HDAC4 (Q6NZM9)
Histone deacetylase 4 (HD4) (EC 3.5.1.98)
Gene: HDAC4

Species: Mus musculus

Source: intact

Category: High-throughput

Confidence: High

Method score Annotation score Interaction score
0.47 0.60 0.536

The method score is based on:

Property Details
Experiments 31040226
Identification Methods affinity chromatography technology, anti bait coimmunoprecipitation
Interaction Type physical association, association

The annotation score is based on:

Property Details
Interacting Pfam domains -
Common GO terms GO:0000122 - negative regulation of transcription by RNA polymerase II
GO:0003677 - DNA binding
GO:0003682 - chromatin binding
GO:0005634 - nucleus
GO:0005654 - nucleoplasm
and 5 others

more...

Homologous interactions 14

Homologous interactions

Color coding for hit scores

1 1620
Mm

1 1076
+ Mm
+ Hs
+ Hs
+ Hs
+ Xl
+ Xl
+ At
+ Mm
+ Mm
+ Hs
+ Hs
+ Hs
+ Hs
+ Hs

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Last updated: 15 Jul 2024