Protein: IRF7
Interferon regulatory factor 7 (IRF-7)

Gene: IRF7
Organism: Mus musculus
Interactions: 22
UniProt ID: P70434

Gene Ontology (top 5):
GO:0000785 - chromatin
GO:0000978 - RNA polymerase II cis-regulatory region sequence-specific DNA binding
GO:0000981 - DNA-binding transcription factor activity, RNA polymerase II-specific
GO:0000987 - cis-regulatory region sequence-specific DNA binding
GO:0002753 - cytoplasmic pattern recognition receptor signaling pathway

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

1000412

IRF7
Interferon regulatory factor 7

2

18

Small-scale

0.754

High

999826

TRAF6
TNF receptor-associated factor 6

3

20

Small-scale

0.656

High

648045

MYD88
Myeloid differentiation primary response protein MyD88

3

20

Small-scale

0.640

High

484853

HXB8
Homeobox protein Hox-B8

1

7

High-throughput

0.541

High

1000413

EMX1
Homeobox protein EMX1

1

9

High-throughput

0.541

High

1000417

TRI35
E3 ubiquitin-protein ligase TRIM35

1

11

Small-scale

0.528

High

312139

IKKB
Inhibitor of nuclear factor kappa-B kinase subunit beta

1

14

Small-scale

0.515

High

1000414

IKKA
Inhibitor of nuclear factor kappa-B kinase subunit alpha

1

15

Small-scale

0.515

High

1000418

RSAD2
S-adenosylmethionine-dependent nucleotide dehydratase RSAD2

1

2

Small-scale

0.515

High

204653

NMI
N-myc-interactor

1

2

Small-scale

0.479

High

312483

NEMO
NF-kappa-B essential modulator

1

2

Small-scale

0.479

High

313117

HDAC3
Histone deacetylase 3

1

5

Small-scale

0.479

High

378386

IFNB
Interferon beta

1

20

Small-scale

0.479

High

456563

IFNA4
Interferon alpha-4

1

20

Small-scale

0.479

High

991474

SUMO1
Small ubiquitin-related modifier 1

1

6

Small-scale

0.479

High

1000415

TGFR2
TGF-beta receptor type-2

1

1

High-throughput

0.479

High

1000419

WWP2
NEDD4-like E3 ubiquitin-protein ligase WWP2

1

2

Small-scale

0.479

High

1000420

FOXO3
Forkhead box protein O3

1

6

Small-scale

0.479

High

1000421

SUMO3
Small ubiquitin-related modifier 3

1

6

Small-scale

0.479

High

1000416

EGLN
Endoglin

1

0

High-throughput

0.458

High

62785

GBP4
Guanylate-binding protein 4

1

9

Small-scale

0.437

High


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Last updated: 11Aug2025