Interactor 1: MTDC (P13995)
Bifunctional methylenetetrahydrofolate dehydrogenase/cyclohydrolase, mitochondrial [Includes: NAD-dependent methylenetetrahydrofolate dehydrogenase (EC 1.5.1.15); Methenyltetrahydrofolate cyclohydrolase (EC 3.5.4.9)]
Gene: MTHFD2
Interactor 2: MTD2L (Q9H903)
Bifunctional methylenetetrahydrofolate dehydrogenase/cyclohydrolase 2, mitochondrial (NADP-dependent methylenetetrahydrofolate dehydrogenase 2-like protein) (MTHFD2-like) [Includes: NAD-dependent methylenetetrahydrofolate dehydrogenase (EC 1.5.1.15) (EC 1.5.1.5); Methenyltetrahydrofolate cyclohydrolase (EC 3.5.4.9)]
Gene: MTHFD2L
Species: Homo sapiens
Source: intact
Category: High-throughput
Confidence: High
| Method score | Annotation score | Interaction score |
|---|---|---|
| 0.65 | 1.00 | 0.811 |
The method score is based on:
The annotation score is based on:
| Property | Details |
|---|---|
| Interacting Pfam domains | THF_DHG_CYH~THF_DHG_CYH, THF_DHG_CYH~THF_DHG_CYH_C, THF_DHG_CYH_C~THF_DHG_CYH_C |
| Common GO terms | GO:0004477 - methenyltetrahydrofolate cyclohydrolase activity GO:0004487 - methylenetetrahydrofolate dehydrogenase (NAD+) activity GO:0004488 - methylenetetrahydrofolate dehydrogenase (NADP+) activity GO:0005739 - mitochondrion GO:0005759 - mitochondrial matrix and 2 others more... |
| Homologous interactions | 5 |
Homologous interactions
Color coding for hit scores 
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Service provided by Combinatics, Japan
Last updated: 15 Jul 2024
