Interactor 1: HSP7C (P11142)
Heat shock cognate 71 kDa protein (EC 3.6.4.10) (Heat shock 70 kDa protein 8) (Heat shock protein family A member 8) (Lipopolysaccharide-associated protein 1) (LAP-1) (LPS-associated protein 1)
Gene: HSPA8

Interactor 2: ENPL (P14625)
Endoplasmin (EC 3.6.4.-) (94 kDa glucose-regulated protein) (GRP-94) (Heat shock protein 90 kDa beta member 1) (Heat shock protein family C member 4) (Tumor rejection antigen 1) (gp96 homolog)
Gene: HSP90B1

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score Annotation score Interaction score
0.38 1.00 0.618

The method score is based on:

Property Details
Experiments 31839598
Identification Methods cross-linking study
Interaction Type physical association

The annotation score is based on:

Property Details
Interacting Pfam domains HATPase_c_3~HSP70, HSP70~HSP90
Common GO terms GO:0003723 - RNA binding
GO:0005524 - ATP binding
GO:0005576 - extracellular region
GO:0005634 - nucleus
GO:0005829 - cytosol
and 9 others

more...

Homologous interactions 10

Homologous interactions

Color coding for hit scores

1 646
Hs

1 803
+ Gg
+ Gg
+ Hs
+ Hs
+ Hs
+ Mm
+ Hs
+ Hs
+ Hs
+ Ce

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Last updated: 11Aug2025