HitPredict

Interactor 1: TRI27 (P14373)
Zinc finger protein RFP (EC 2.3.2.27) (RING finger protein 76) (Ret finger protein) (Tripartite motif-containing protein 27)
Gene: TRIM27

Interactor 2: LNX1 (Q8TBB1)
E3 ubiquitin-protein ligase LNX (EC 2.3.2.27) (Ligand of Numb-protein X 1) (Numb-binding protein 1) (PDZ domain-containing RING finger protein 2) (RING-type E3 ubiquitin transferase LNX)
Gene: LNX1

Species: Homo sapiens

Source: intact

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.71	1.00	0.843

Property	Details
Experiments	29121065, 32296183, unassigned1304
Identification Methods	affinity chromatography technology, two hybrid, validated two hybrid, two hybrid array, two hybrid prey pooling approach
Interaction Type	physical association, direct interaction

Property	Details
Interacting Pfam domains	zf-B_box~zf-C3HC4
Common GO terms	GO:0004842 - ubiquitin-protein transferase activity GO:0005737 - cytoplasm GO:0046872 - metal ion binding
Homologous interactions	7

Homologous interactions

Color coding for hit scores

	1 513 Hs			1 728
+	Hs
		585019 RO52_HUMAN (1-500): 2.33e-160: 465: 36.78		LNX1_HUMAN (1-728): 1.08e-139: 429: 100.00
+	Hs
		1252493 TRI39_HUMAN (7-494): 3.22e-158: 462: 37.60		LNX1_HUMAN (1-728): 1.08e-139: 429: 100.00
+	Hs
		1149890 TRI68_HUMAN (1-496): 2.82e-143: 422: 34.96		LNX1_HUMAN (1-728): 1.08e-139: 429: 100.00
+	Hs
		1115440 TRI60_HUMAN (1-496): 6.27e-142: 418: 30.58		LNX1_HUMAN (1-728): 1.08e-139: 429: 100.00
+	Hs
		1252534 TRI10_HUMAN (1-480): 7.29e-125: 375: 34.36		LNX1_HUMAN (1-728): 1.08e-139: 429: 100.00
+	Hs
		1204896 TRI50_HUMAN (1-488): 4.24e-121: 365: 27.53		LNX1_HUMAN (1-728): 1.08e-139: 429: 100.00
+	Hs
		1020183 TRI72_HUMAN (1-497): 1.41e-104: 322: 26.23		PTN13_HUMAN (455-725): 4.02e-23: 107: 15.44