HitPredict

Interactor 1: ENPL (P14625)
Endoplasmin (94 kDa glucose-regulated protein) (GRP-94) (Heat shock protein 90 kDa beta member 1) (Heat shock protein family C member 4) (Tumor rejection antigen 1) (gp96 homolog)
Gene: HSP90B1

Interactor 2: UFO (P30530)
Tyrosine-protein kinase receptor UFO (EC 2.7.10.1) (AXL oncogene)
Gene: AXL

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.60	0.479

Property	Details
Experiments	35384245
Identification Methods	proximity labelling technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005524 - ATP binding GO:0043066 - negative regulation of apoptotic process GO:0070062 - extracellular exosome
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 803 Hs			1 894
+	Hs
		437923 HS90B_HUMAN (75-783): 0: 997: 46.54		UFO_HUMAN (1-894): 0: 780: 100.00
+	Hs
		438029 HS90B_HUMAN (75-783): 0: 997: 46.54		EPHA4_HUMAN (2-836): 0: 637: 19.40
+	Hs
		438028 HS90B_HUMAN (75-783): 0: 997: 46.54		EPHB1_HUMAN (2-833): 0: 621: 20.70
+	Hs
		437918 HS90B_HUMAN (75-783): 0: 997: 46.54		EPHA2_HUMAN (3-837): 0: 604: 19.66
+	Hs
		438114 HS90B_HUMAN (75-783): 0: 997: 46.54		MERTK_HUMAN (7-861): 0: 588: 40.53
+	Hs
		538261 ENPL_HUMAN (1-803): 0: 1073: 100.00		EPHAA_HUMAN (2-837): 2.59e-158: 491: 18.61
+	Hs
		437892 HS90B_HUMAN (75-783): 0: 997: 46.54		EPHA1_HUMAN (1-837): 0: 555: 20.58
+	Hs
		411287 ENPL_HUMAN (1-803): 0: 1073: 100.00		INSR_HUMAN (272-851): 1.65e-136: 443: 27.97
+	Rn
		544887 ENPL_RAT (1-803): 0: 1055: 95.03		INSR_RAT (276-851): 1.26e-134: 437: 27.83
+	Hs
		437946 HS90B_HUMAN (75-783): 0: 997: 46.54		TIE1_HUMAN (16-809): 4.24e-158: 494: 21.82
+	Hs
		538204 ENPL_HUMAN (1-803): 0: 1073: 100.00		RON_HUMAN (518-810): 1.36e-56: 214: 40.47
+	Hs
		437816 HS90B_HUMAN (75-783): 0: 997: 46.54		MET_HUMAN (536-799): 3.42e-66: 243: 45.90
+	Hs
		438096 HS90B_HUMAN (75-783): 0: 997: 46.54		FAK1_HUMAN (527-851): 1.72e-56: 213: 36.83
+	Hs
		435523 ENPL_HUMAN (1-803): 0: 1073: 100.00		IGF1R_HUMAN (234-385): 4.65e-12: 72.4: 18.07
+	Hs
		437897 HS90B_HUMAN (75-783): 0: 997: 46.54		FGFR3_HUMAN (2-135): 5.06e-15: 81.7: 14.29
+	Hs
		438100 HS90B_HUMAN (75-783): 0: 997: 46.54		TYRO3_HUMAN (8-328): 1.16e-14: 80.5: 16.42
+	Hs
		169160 HS90B_HUMAN (75-783): 0: 997: 46.54		MUSK_HUMAN (2-147): 3.72e-14: 79: 11.26
+	Hs
		437838 HS90B_HUMAN (75-783): 0: 997: 46.54		FGFR1_HUMAN (10-149): 2.65e-12: 72.9: 15.69
+	Hs
		435497 HS90B_HUMAN (75-783): 0: 997: 46.54		IGF1R_HUMAN (234-385): 4.65e-12: 72.4: 18.07
+	Hs
		169159 HS90A_HUMAN (60-783): 0: 990: 45.34		MUSK_HUMAN (2-147): 3.72e-14: 79: 11.26