HitPredict

Interactor 1: ENPL (P14625)
Endoplasmin (94 kDa glucose-regulated protein) (GRP-94) (Heat shock protein 90 kDa beta member 1) (Heat shock protein family C member 4) (Tumor rejection antigen 1) (gp96 homolog)
Gene: HSP90B1

Interactor 2: EMC2 (Q15006)
ER membrane protein complex subunit 2 (Tetratricopeptide repeat protein 35) (TPR repeat protein 35)
Gene: EMC2

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.57	0.60	0.586

Property	Details
Experiments	32296183, 27342126
Identification Methods	two hybrid, affinity chromatography technology
Interaction Type	direct interaction, physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005783 - endoplasmic reticulum GO:0005789 - endoplasmic reticulum membrane GO:0034975 - protein folding in endoplasmic reticulum
Homologous interactions	6

Homologous interactions

Color coding for hit scores

	1 803 Hs			1 297
+	Hs
		174598 ENPL_HUMAN (1-803): 0: 1073: 100.00		OGT1_HUMAN (21-213): 4.65e-40: 150: 11.40
+	Hs
		174561 HS90B_HUMAN (75-783): 0: 997: 46.54		OGT1_HUMAN (21-213): 4.65e-40: 150: 11.40
+	Hs
		174556 HS90A_HUMAN (60-783): 0: 990: 45.34		OGT1_HUMAN (21-213): 4.65e-40: 150: 11.40
+	Hs
		431797 HS90A_HUMAN (60-783): 0: 990: 45.34		IFT88_HUMAN (87-213): 1.23e-09: 60.9: 14.93
+	Ca
		804535 HSP90_CANAL (70-783): 0: 879: 46.45		Q5ADP3_CANAL (15-296): 7.52e-36: 138: 10.29
+	Hs
		1062619 Q96GW1_HUMAN (1-311): 0: 550: 100.00		EMC2_HUMAN (1-297): 1.09e-73: 229: 100.00