HitPredict

Interactor 1: ENPL (P14625)
Endoplasmin (94 kDa glucose-regulated protein) (GRP-94) (Heat shock protein 90 kDa beta member 1) (Heat shock protein family C member 4) (Tumor rejection antigen 1) (gp96 homolog)
Gene: HSP90B1

Interactor 2: FBX6 (Q9NRD1)
F-box only protein 6 (F-box protein that recognizes sugar chains 2) (F-box/G-domain protein 2)
Gene: FBXO6

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.56	0.60	0.584

Property	Details
Experiments	32409323, 22268729
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005829 - cytosol GO:0036503 - ERAD pathway
Homologous interactions	5

Homologous interactions

Color coding for hit scores

	1 803 Hs			1 293
+	Hs
		438556 HS90B_HUMAN (75-783): 0: 997: 46.54		FBX6_HUMAN (1-293): 1.15e-178: 495: 100.00
+	Hs
		432291 HS90A_HUMAN (60-783): 0: 990: 45.34		FBX6_HUMAN (1-293): 1.15e-178: 495: 100.00
+	Hs
		432146 HS90A_HUMAN (60-783): 0: 990: 45.34		FBX17_HUMAN (12-262): 4.9e-118: 342: 33.83
+	Hs
		438372 HS90B_HUMAN (75-783): 0: 997: 46.54		FBX27_HUMAN (26-262): 8.01e-114: 331: 40.80
+	Hs
		432080 HS90A_HUMAN (60-783): 0: 990: 45.34		FBX27_HUMAN (26-262): 8.01e-114: 331: 40.80