HitPredict

Interactor 1: ENPL (P14625)
Endoplasmin (94 kDa glucose-regulated protein) (GRP-94) (Heat shock protein 90 kDa beta member 1) (Heat shock protein family C member 4) (Tumor rejection antigen 1) (gp96 homolog)
Gene: HSP90B1

Interactor 2: SGT1 (Q9Y2Z0)
Protein SGT1 homolog (Protein 40-6-3) (Sgt1) (Suppressor of G2 allele of SKP1 homolog)
Gene: SUGT1

Species: Homo sapiens

Source: innatedb

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.68	0.60	0.640

Property	Details
Experiments	27249023, 17466273, 16501598
Identification Methods	affinity chromatography technology, solid phase assay, anti tag coimmunoprecipitation
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005634 - nucleus GO:0005829 - cytosol GO:0032991 - protein-containing complex
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 803 Hs			1 365
+	Hs
		438644 HS90B_HUMAN (75-783): 0: 997: 46.54		SGT1_HUMAN (1-365): 2.37e-88: 272: 100.00
+	Hs
		432387 HS90A_HUMAN (60-783): 0: 990: 45.34		SGT1_HUMAN (1-365): 2.37e-88: 272: 100.00
+	Mm
		435924 ENPL_MOUSE (1-803): 0: 1062: 96.64		PPP5_MOUSE (9-202): 3.13e-39: 147: 16.58
+	Hs
		538217 ENPL_HUMAN (1-803): 0: 1073: 100.00		DNJC3_HUMAN (6-326): 2.67e-25: 108: 15.69
+	Hs
		174598 ENPL_HUMAN (1-803): 0: 1073: 100.00		OGT1_HUMAN (48-303): 5e-18: 87.6: 9.51
+	Mm
		513680 HS90B_MOUSE (75-783): 0: 998: 46.26		PPP5_MOUSE (9-202): 3.13e-39: 147: 16.58
+	Hs
		213454 HS90B_HUMAN (75-783): 0: 997: 46.54		SGTA_HUMAN (6-171): 3.42e-40: 146: 20.96
+	Hs
		438021 HS90B_HUMAN (75-783): 0: 997: 46.54		PPP5_HUMAN (9-242): 1.39e-38: 145: 14.71
+	Hs
		213451 HS90A_HUMAN (60-783): 0: 990: 45.34		SGTA_HUMAN (6-171): 3.42e-40: 146: 20.96
+	Hs
		538353 ENPL_HUMAN (1-803): 0: 1073: 100.00		SGTB_HUMAN (91-296): 3.48e-10: 62.2: 12.14
+	Hs
		111935 K9JA46_HUMAN (60-783): 0: 990: 45.34		PPP5_HUMAN (9-242): 1.39e-38: 145: 14.71
+	Hs
		431681 HS90A_HUMAN (60-783): 0: 990: 45.34		PPP5_HUMAN (9-242): 1.39e-38: 145: 14.71
+	Mm
		432427 HS90A_MOUSE (60-783): 0: 985: 45.28		PPP5_MOUSE (9-202): 3.13e-39: 147: 16.58
+	Hs
		438533 HS90B_HUMAN (75-783): 0: 997: 46.54		RPAP3_HUMAN (3-129): 5.92e-27: 114: 14.17
+	Hs
		432268 HS90A_HUMAN (60-783): 0: 990: 45.34		RPAP3_HUMAN (3-129): 5.92e-27: 114: 14.17
+	Hs
		431774 HS90A_HUMAN (60-783): 0: 990: 45.34		SPAG1_HUMAN (2-339): 1.63e-24: 107: 12.50
+	Hs
		174561 HS90B_HUMAN (75-783): 0: 997: 46.54		OGT1_HUMAN (48-303): 5e-18: 87.6: 9.51
+	Hs
		174556 HS90A_HUMAN (60-783): 0: 990: 45.34		OGT1_HUMAN (48-303): 5e-18: 87.6: 9.51
+	Hs
		297025 HS90B_HUMAN (75-783): 0: 997: 46.54		TOM70_HUMAN (3-221): 1.5e-09: 61.4: 9.29
+	Hs
		297024 HS90A_HUMAN (60-783): 0: 990: 45.34		TOM70_HUMAN (3-221): 1.5e-09: 61.4: 9.29