HitPredict

Interactor 1: MYL6B (P14649)
Myosin light chain 6B (Myosin light chain 1 slow-twitch muscle A isoform) (MLC1sa) (Smooth muscle and nonmuscle myosin light chain alkali 6B)
Gene: MYL6B

Interactor 2: MY18A (Q92614)
Unconventional myosin-XVIIIa (Molecule associated with JAK3 N-terminus) (MAJN) (Myosin containing a PDZ domain) (Surfactant protein receptor SP-R210) (SP-R210)
Gene: MYO18A

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.60	0.60	0.601

Property	Details
Experiments	26496610, 35271311
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0016460 - myosin II complex
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 208 Hs			1 2054
+	Hs
		891573 MYL6_HUMAN (60-207): 5.77e-70: 211: 81.76		MY18A_HUMAN (1-2054): 0: 1279: 100.00
+	Hs
		521686 MYL4_HUMAN (52-207): 1.48e-63: 197: 69.62		MY18A_HUMAN (1-2054): 0: 1279: 100.00
+	Hs
		441675 MYL3_HUMAN (52-207): 3.62e-63: 195: 68.99		MY18A_HUMAN (1-2054): 0: 1279: 100.00
+	Hs
		484173 CALM3_HUMAN (55-133): 5.33e-14: 68.1: 27.85		MY18A_HUMAN (1-2054): 0: 1279: 100.00
+	Dm
		906697 CALM_DROME (57-207): 1.21e-59: 185: 43.42		MYO7A_DROME (347-1359): 0: 824: 21.39
+	Dm
		870146 MLC2_DROME (61-207): 1.41e-48: 157: 53.74		MYO7A_DROME (347-1359): 0: 824: 21.39
+	Gg
		361265 MYL6_CHICK (60-207): 1.53e-66: 203: 74.32		MYH11_CHICK (1206-2044): 7.34e-58: 224: 16.17
+	Hs
		724737 MYL6_HUMAN (60-207): 5.77e-70: 211: 81.76		MYH9_HUMAN (1141-1989): 2.8e-46: 186: 14.96
+	Hs
		648467 CALL3_HUMAN (60-207): 2.54e-65: 199: 44.97		MYH9_HUMAN (1141-1989): 2.8e-46: 186: 14.96
+	Hs
		441665 MYL3_HUMAN (52-207): 3.62e-63: 195: 68.99		MYH9_HUMAN (1141-1989): 2.8e-46: 186: 14.96
+	Hs
		538642 MYL6B_HUMAN (1-208): 2.72e-52: 168: 100.00		MYH9_HUMAN (1141-1989): 2.8e-46: 186: 14.96
+	Dm
		870145 MLC2_DROME (61-207): 1.41e-48: 157: 53.74		MYSN_DROME (1218-1932): 2.19e-38: 160: 23.06
+	Hs
		728458 MYL6_HUMAN (60-207): 5.77e-70: 211: 81.76		MYH11_HUMAN (1684-2053): 3.04e-19: 97.5: 15.00
+	Hs
		725124 MYL6_HUMAN (60-207): 5.77e-70: 211: 81.76		MYH10_HUMAN (1178-1641): 2.73e-18: 94.4: 14.56
+	Hs
		409452 MYL1_HUMAN (49-208): 9.78e-65: 200: 69.38		MYH10_HUMAN (1178-1641): 2.73e-18: 94.4: 14.56
+	Hs
		441666 MYL3_HUMAN (52-207): 3.62e-63: 195: 68.99		MYH10_HUMAN (1178-1641): 2.73e-18: 94.4: 14.56
+	Hs
		891551 MYL6_HUMAN (60-207): 5.77e-70: 211: 81.76		MYH14_HUMAN (1253-1933): 3.46e-11: 71.2: 19.08
+	Hs
		441674 MYL3_HUMAN (52-207): 3.62e-63: 195: 68.99		MYH14_HUMAN (1253-1933): 3.46e-11: 71.2: 19.08
+	Hs
		538643 MYL6B_HUMAN (1-208): 2.72e-52: 168: 100.00		MYH10_HUMAN (1178-1641): 2.73e-18: 94.4: 14.56
+	Hs
		538680 MYL6B_HUMAN (1-208): 2.72e-52: 168: 100.00		MYH14_HUMAN (1253-1933): 3.46e-11: 71.2: 19.08