HitPredict

Interactor 1: RSMB (P14678)
Small nuclear ribonucleoprotein-associated proteins B and B' (snRNP-B) (Sm protein B/B') (Sm-B/B') (SmB/B')
Gene: SNRPB

Interactor 2: RNPC3 (Q96LT9)
RNA-binding region-containing protein 3 (RNA-binding motif protein 40) (RNA-binding protein 40) (U11/U12 small nuclear ribonucleoprotein 65 kDa protein) (U11/U12 snRNP 65 kDa protein) (U11/U12-65K)
Gene: RNPC3

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.65	0.60	0.628

Property	Details
Experiments	33961781, 35271311
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0000398 - mRNA splicing, via spliceosome GO:0005634 - nucleus GO:0005654 - nucleoplasm GO:0005689 - U12-type spliceosomal complex GO:0008380 - RNA splicing
Homologous interactions	7

Homologous interactions

Color coding for hit scores

	1 240 Hs			1 517
+	Hs
		927999 RSMN_HUMAN (1-212): 6.6e-39: 136: 92.93		RNPC3_HUMAN (1-517): 0: 563: 100.00
+	Hs
		441225 RSMB_HUMAN (1-168): 6.54e-43: 146: 100.00		RU2B_HUMAN (417-513): 4.32e-35: 132: 26.80
+	Hs
		446497 RSMB_HUMAN (1-168): 6.54e-43: 146: 100.00		SNRPA_HUMAN (417-513): 2.71e-33: 129: 25.77
+	Hs
		441262 RSMN_HUMAN (1-212): 6.6e-39: 136: 92.93		RU2B_HUMAN (417-513): 4.32e-35: 132: 26.80
+	Hs
		539198 RSMB_HUMAN (1-168): 6.54e-43: 146: 100.00		SF3B6_HUMAN (415-516): 3.93e-32: 121: 22.55
+	Hs
		446577 RSMN_HUMAN (1-212): 6.6e-39: 136: 92.93		SNRPA_HUMAN (417-513): 2.71e-33: 129: 25.77
+	Dm
		795441 RSMB_DROME (1-205): 2.49e-31: 115: 60.49		SNRPA_DROME (418-513): 6.37e-28: 112: 23.96