HitPredict

Interactor 1: RALB (P11234)
Ras-related protein Ral-B (EC 3.6.5.2)
Gene: RALB

Interactor 2: EXOC2 (Q96KP1)
Exocyst complex component 2 (Exocyst complex component Sec5)
Gene: EXOC2

Species: Homo sapiens

Source: intact

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.85	1.00	0.925

Property	Details
Experiments	14525976, 24056301, 21241894, 27173435, 17018283
Identification Methods	two hybrid, affinity chromatography technology, pull down, tandem affinity purification
Interaction Type	direct interaction, physical association, association

Property	Details
Interacting Pfam domains	Ras~TIG
Common GO terms	GO:0005886 - plasma membrane
Homologous interactions	8

Homologous interactions

Color coding for hit scores

	1 206 Hs			1 924
+	Hs
		539838 RALA_HUMAN (1-206): 1.43e-86: 255: 81.64		EXOC2_HUMAN (1-924): 0: 1074: 100.00
+	Hs
		976487 RB11A_HUMAN (5-204): 4.54e-73: 221: 29.44		EXOC2_HUMAN (1-924): 0: 1074: 100.00
+	Dm
		874116 RALA_DROME (13-206): 2.8e-92: 270: 75.26		EXOC2_DROME (8-919): 0: 846: 32.80
+	Dm
		1379632 Q962I2_DROME (13-186): 1.09e-89: 263: 78.16		EXOC2_DROME (8-919): 0: 846: 32.80
+	Hs
		976640 RB11A_HUMAN (5-204): 4.54e-73: 221: 29.44		VPS51_HUMAN (150-899): 1.21e-173: 525: 14.16
+	Hs
		374996 RASH_HUMAN (27-181): 3.77e-49: 160: 52.90		VPS51_HUMAN (150-899): 1.21e-173: 525: 14.16
+	Hs
		374265 RASN_HUMAN (27-191): 8.81e-49: 159: 50.00		VPS51_HUMAN (150-899): 1.21e-173: 525: 14.16
+	Hs
		376068 RASK_HUMAN (27-198): 2.82e-47: 155: 50.00		VPS51_HUMAN (150-899): 1.21e-173: 525: 14.16