HitPredict

Interactor 1: IL1R1 (P14778)
Interleukin-1 receptor type 1 (IL-1R-1) (IL-1RT-1) (IL-1RT1) (EC 3.2.2.6) (CD121 antigen-like family member A) (Interleukin-1 receptor alpha) (IL-1R-alpha) (Interleukin-1 receptor type I) (p80) (CD antigen CD121a) [Cleaved into: Interleukin-1 receptor type 1, membrane form (mIL-1R1) (mIL-1RI); Interleukin-1 receptor type 1, soluble form (sIL-1R1) (sIL-1RI)]
Gene: IL1R1

Interactor 2: CILK1 (Q9UPZ9)
Serine/threonine-protein kinase ICK (EC 2.7.11.1) (Ciliogenesis associated kinase 1) (Intestinal cell kinase) (hICK) (Laryngeal cancer kinase 2) (LCK2) (MAK-related kinase) (MRK)
Gene: CILK1

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.65	0.50	0.574

Property	Details
Experiments	28514442, 33961781
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	-
Homologous interactions	7

Homologous interactions

Color coding for hit scores

	1 569 Hs			1 632
+	Hs
		507863 FGFR1_HUMAN (9-375): 8.03e-60: 214: 16.23		CDK2_HUMAN (1-290): 1.28e-143: 420: 38.91
+	Hs
		609180 FGFR3_HUMAN (28-362): 6.25e-59: 212: 17.33		CDK2_HUMAN (1-290): 1.28e-143: 420: 38.91
+	Hs
		507867 FGFR1_HUMAN (9-375): 8.03e-60: 214: 16.23		MARK3_HUMAN (1-618): 2.16e-132: 407: 18.97
+	Hs
		414702 FGFR1_HUMAN (9-375): 8.03e-60: 214: 16.23		CDK1_HUMAN (1-289): 3.13e-136: 401: 39.93
+	Hs
		414738 FGFR3_HUMAN (28-362): 6.25e-59: 212: 17.33		CDK1_HUMAN (1-289): 3.13e-136: 401: 39.93
+	Hs
		625665 ROBO1_HUMAN (20-437): 4.03e-17: 87.5: 10.86		CDK2_HUMAN (1-290): 1.28e-143: 420: 38.91
+	Hs
		625528 TITIN_HUMAN (34-319): 9.03e-09: 60.9: 9.43		CDK2_HUMAN (1-290): 1.28e-143: 420: 38.91