Protein: BORG4
Cdc42 effector protein 4 (Binder of Rho GTPases 4)

Gene: BORG4, CDC42EP4
Organism: Homo sapiens
Interactions: 80
UniProt ID: Q9H3Q1

Gene Ontology (top 5):
GO:0003723 - RNA binding
GO:0005737 - cytoplasm
GO:0005829 - cytosol
GO:0005856 - cytoskeleton
GO:0005886 - plasma membrane

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

955584

CDC42
Cell division control protein 42 homolog

4

20

High-throughput

0.900

High

374192

RASN
GTPase NRas

2

9

High-throughput

0.754

High

374926

RASH
GTPase HRas

2

6

High-throughput

0.754

High

375948

RASK
GTPase KRas

2

9

High-throughput

0.754

High

978300

RHOB
Rho-related GTP-binding protein RhoB

2

20

High-throughput

0.754

High

1432839

SEP10
Septin-10

5

14

High-throughput

0.712

High

1432842

SEPT9
Septin-9

5

15

High-throughput

0.712

High

1006708

SRPK2
SRSF protein kinase 2

1

2

High-throughput

0.710

High

1432845

RBL2B
Rab-like protein 2B

1

2

High-throughput

0.691

High

1121197

SEPT6
Septin-6

4

15

High-throughput

0.691

High

1156417

SEPT7
Septin-7

4

15

High-throughput

0.691

High

1406706

SEPT5
Septin-5

4

14

High-throughput

0.691

High

1432841

SEPT3
Neuronal-specific septin-3

4

14

High-throughput

0.691

High

210505

SEPT4
Septin-4

4

15

High-throughput

0.683

High

1137009

SEPT2
Septin-2

3

14

High-throughput

0.667

High

1365289

SEPT8
Septin-8

3

15

High-throughput

0.667

High

1432837

SEP11
Septin-11

3

15

High-throughput

0.667

High

1256422

SEP14
Septin-14

2

15

High-throughput

0.628

High

126798

RHOD
Rho-related GTP-binding protein RhoD

1

20

High-throughput

0.618

High

581284

RAC2
Ras-related C3 botulinum toxin substrate 2

1

19

High-throughput

0.618

High

601442

RHOQ
Rho-related GTP-binding protein RhoQ

1

20

High-throughput

0.618

High

953669

RAC3
Ras-related C3 botulinum toxin substrate 3

1

20

High-throughput

0.618

High

962473

RHOA
Transforming protein RhoA

1

19

High-throughput

0.618

High

988702

RAC1
Ras-related C3 botulinum toxin substrate 1

1

20

High-throughput

0.618

High

1015780

RHOG
Rho-related GTP-binding protein RhoG

1

19

High-throughput

0.618

High

1145108

RAB35
Ras-related protein Rab-35

1

1

High-throughput

0.618

High

1151873

RHOH
Rho-related GTP-binding protein RhoH

1

20

High-throughput

0.618

High

1270992

RHOU
Rho-related GTP-binding protein RhoU

1

20

High-throughput

0.618

High

1396626

RHOV
Rho-related GTP-binding protein RhoV

1

20

High-throughput

0.618

High

1432832

RHOJ
Rho-related GTP-binding protein RhoJ

1

20

High-throughput

0.618

High

1432833

RHOF
Rho-related GTP-binding protein RhoF

1

20

High-throughput

0.618

High

1123113

FHL2
Four and a half LIM domains protein 2

3

1

High-throughput

0.609

High

1316987

FAM9B
Protein FAM9B

2

0

High-throughput

0.601

High

540674

LAMP1
Lysosome-associated membrane glycoprotein 1

2

3

High-throughput

0.584

High

975241

ARF6
ADP-ribosylation factor 6

2

1

High-throughput

0.584

High

1358855

KBTB7
Kelch repeat and BTB domain-containing protein 7

2

0

High-throughput

0.576

High

1402577

SRPK1
SRSF protein kinase 1

1

2

High-throughput

0.575

High

290729

SURF6
Surfeit locus protein 6

1

0

High-throughput

0.513

High

1295212

HOME1
Homer protein homolog 1

1

0

High-throughput

0.513

High

1432834

E41L5
Band 4.1-like protein 5

1

0

High-throughput

0.513

High

1432836

RN146
E3 ubiquitin-protein ligase RNF146

1

0

High-throughput

0.513

High

1432838

CALL5
Calmodulin-like protein 5

1

0

High-throughput

0.513

High

221187

SPY2
Protein sprouty homolog 2

1

0

High-throughput

0.493

High

843979

HD
Huntingtin

1

0

High-throughput

0.493

High

1429345

SPRTN
DNA-dependent metalloprotease SPRTN

1

1

High-throughput

0.489

High

1432835

WDR6
tRNA

1

1

High-throughput

0.481

High

423154

A4
Amyloid-beta precursor protein

1

0

High-throughput

0.480

High

189838

STX7
Syntaxin-7

1

1

High-throughput

0.479

High

463766

LYN
Tyrosine-protein kinase Lyn

1

1

High-throughput

0.479

High

556340

CADH1
Cadherin-1

1

1

High-throughput

0.479

High

580696

AMPN
Aminopeptidase N

1

1

High-throughput

0.479

High

710489

EPHA2
Ephrin type-A receptor 2

1

3

High-throughput

0.479

High

715770

MARCS
Myristoylated alanine-rich C-kinase substrate

1

1

High-throughput

0.479

High

845801

MUC18
Cell surface glycoprotein MUC18

1

1

High-throughput

0.479

High

935124

TERA
Transitional endoplasmic reticulum ATPase

1

1

High-throughput

0.479

High

941840

ARL4C
ADP-ribosylation factor-like protein 4C

1

6

High-throughput

0.479

High

1041282

CAV1
Caveolin-1

1

1

High-throughput

0.479

High

1049775

1433F
14-3-3 protein eta

1

8

High-throughput

0.479

High

1115425

CUL4B
Cullin-4B

1

1

High-throughput

0.479

High

1159841

OCLN
Occludin

1

1

High-throughput

0.479

High

1233479

LTOR1
Ragulator complex protein LAMTOR1

1

1

High-throughput

0.479

High

1326513

ARL14
ADP-ribosylation factor-like protein 14

1

3

High-throughput

0.479

High

1432840

ZRAN1
Ubiquitin thioesterase ZRANB1

1

1

High-throughput

0.479

High

1348500

LNX1
E3 ubiquitin-protein ligase LNX

1

0

Small-scale

0.460

High

1432843

ALK
ALK tyrosine kinase receptor

1

0

High-throughput

0.458

High

1432846

RPC8
DNA-directed RNA polymerase III subunit RPC8

1

0

High-throughput

0.458

High

1245632

Q6PKC6
tRNA

1

1

High-throughput

0.457

High

551259

PCNA
Proliferating cell nuclear antigen

1

1

High-throughput

0.437

High

1367262

ESR2
Estrogen receptor beta

1

1

High-throughput

0.437

High

1381964

CK052
Uncharacterized protein C11orf52

1

1

High-throughput

0.437

High

332340

ATE1
Arginyl-tRNA--protein transferase 1

1

0

High-throughput

0.426

High

1359805

RT4I1
NAD(P)H oxidoreductase RTN4IP1, mitochondrial

3

0

High-throughput

0.347

High

1397874

KLH15
Kelch-like protein 15

3

0

High-throughput

0.347

High

1248738

SBSN
Suprabasin

1

0

High-throughput

0.279

Low

1322241

RBFA
Putative ribosome-binding factor A, mitochondrial

1

0

High-throughput

0.279

Low

1417224

TGT
Queuine tRNA-ribosyltransferase catalytic subunit 1

1

0

High-throughput

0.279

Low

1432844

SNX12
Sorting nexin-12

1

0

High-throughput

0.279

Low

553870

KCRU
Creatine kinase U-type, mitochondrial

1

0

High-throughput

0.249

Low

946529

YBEY
Endoribonuclease YbeY

1

0

High-throughput

0.249

Low

516867

RPAC2
DNA-directed RNA polymerases I and III subunit RPAC2

1

0

High-throughput

0.232

Low


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Last updated: 11Aug2025