HitPredict

Interactor 1: MMP9 (P14780)
Matrix metalloproteinase-9 (MMP-9) (EC 3.4.24.35) (92 kDa gelatinase) (92 kDa type IV collagenase) (Gelatinase B) (GELB) [Cleaved into: 67 kDa matrix metalloproteinase-9; 82 kDa matrix metalloproteinase-9]
Gene: MMP9

Interactor 2: SCAR3 (Q6AZY7)
Scavenger receptor class A member 3 (Cellular stress response gene protein)
Gene: SCARA3

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.65	0.50	0.574

Property	Details
Experiments	28514442, 33961781
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	-
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 707 Hs			1 606
+	Hs
		540432 MMP9_HUMAN (1-707): 0: 862: 100.00		COL12_HUMAN (18-508): 5.46e-137: 418: 27.05
+	Hs
		436005 MMP9_HUMAN (1-707): 0: 862: 100.00		CO1A2_HUMAN (461-605): 1.13e-18: 92.5: 27.43
+	Hs
		517985 MMP9_HUMAN (1-707): 0: 862: 100.00		CO6A2_HUMAN (546-606): 4.63e-13: 74.4: 40.98
+	Hs
		441053 MMP9_HUMAN (1-707): 0: 862: 100.00		CO4A2_HUMAN (446-605): 2.09e-12: 72.5: 24.34
+	Hs
		540416 MMP9_HUMAN (1-707): 0: 862: 100.00		SFTPD_HUMAN (463-567): 7.6e-13: 72.4: 45.71
+	Hs
		358650 MMP9_HUMAN (1-707): 0: 862: 100.00		CO4A1_HUMAN (461-573): 1.45e-10: 66.7: 29.31
+	Hs
		358595 MMP9_HUMAN (1-707): 0: 862: 100.00		CO2A1_HUMAN (478-602): 2.69e-09: 62.4: 35.11
+	Hs
		517917 MMP9_HUMAN (1-707): 0: 862: 100.00		CO6A1_HUMAN (437-501): 3.5e-09: 62.1: 28.99
+	Hs
		436002 MMP3_HUMAN (8-272): 4.38e-93: 299: 37.46		CO1A2_HUMAN (461-605): 1.13e-18: 92.5: 27.43
+	Hs
		372723 MMP1_HUMAN (31-238): 9.64e-87: 282: 42.67		CO1A2_HUMAN (461-605): 1.13e-18: 92.5: 27.43
+	Hs
		436012 MMP8_HUMAN (35-295): 3.17e-81: 267: 32.01		CO1A2_HUMAN (461-605): 1.13e-18: 92.5: 27.43
+	Hs
		436025 MMP16_HUMAN (45-280): 2.33e-72: 248: 32.35		CO1A2_HUMAN (461-605): 1.13e-18: 92.5: 27.43
+	Hs
		436022 MMP14_HUMAN (33-254): 2.47e-70: 241: 32.43		CO1A2_HUMAN (461-605): 1.13e-18: 92.5: 27.43
+	Hs
		436024 MMP15_HUMAN (45-279): 2.87e-67: 235: 31.02		CO1A2_HUMAN (461-605): 1.13e-18: 92.5: 27.43
+	Hs
		436001 MMP2_HUMAN (576-707): 2.91e-20: 97.5: 15.71		CO1A2_HUMAN (461-605): 1.13e-18: 92.5: 27.43
+	Hs
		439222 MMP2_HUMAN (576-707): 2.91e-20: 97.5: 15.71		CO6A2_HUMAN (546-606): 4.63e-13: 74.4: 40.98
+	Hs
		439220 MMP2_HUMAN (576-707): 2.91e-20: 97.5: 15.71		CO4A2_HUMAN (446-605): 2.09e-12: 72.5: 24.34
+	Hs
		358647 MMP2_HUMAN (576-707): 2.91e-20: 97.5: 15.71		CO4A1_HUMAN (461-573): 1.45e-10: 66.7: 29.31
+	Hs
		358587 MMP2_HUMAN (576-707): 2.91e-20: 97.5: 15.71		CO2A1_HUMAN (478-602): 2.69e-09: 62.4: 35.11
+	Hs
		439221 MMP2_HUMAN (576-707): 2.91e-20: 97.5: 15.71		CO6A1_HUMAN (437-501): 3.5e-09: 62.1: 28.99