Interactor 1: KRAF1 (P11346)
Raf homolog serine/threonine-protein kinase Raf (D-Raf) (dRAF-1) (EC 2.7.11.1) (Protein pole-hole)
Gene: Raf
Interactor 2: CDC37 (Q24276)
Hsp90 co-chaperone Cdc37 (Hsp90 chaperone protein kinase-targeting subunit) (Protein enhancer of sevenless 3B)
Gene: CDC37
Species: Drosophila melanogaster
Source: biogrid
Category: High-throughput
Confidence: High
| Method score | Annotation score | Interaction score |
|---|---|---|
| 0.38 | 1.00 | 0.618 |
The method score is based on:
| Property | Details |
|---|---|
| Experiments | 22028469 |
| Identification Methods | affinity chromatography technology |
| Interaction Type | physical association |
The annotation score is based on:
| Property | Details |
|---|---|
| Interacting Pfam domains | CDC37_M~PK_Tyr_Ser-Thr, CDC37_N~PK_Tyr_Ser-Thr |
| Common GO terms | GO:0005737 - cytoplasm GO:0070374 - positive regulation of ERK1 and ERK2 cascade |
| Homologous interactions | 9 |
Homologous interactions
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Service provided by Combinatics, Japan
Last updated: 11Aug2025
