HitPredict

Interactor 1: NSP1 (P14907)
Nucleoporin NSP1 (Nuclear pore protein NSP1) (Nucleoskeletal-like protein) (p110)
Gene: NSP1

Interactor 2: IMB4 (P40069)
Importin subunit beta-4 (Importin-123) (Karyopherin subunit beta-4) (Karyopherin-123) (Ran-binding protein YRB4)
Gene: KAP123

Species: Saccharomyces cerevisiae S288C

Source: biogrid

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.69	0.60	0.646

Property	Details
Experiments	17897934, 12169684, 22357553
Identification Methods	affinity chromatography technology, pull down
Interaction Type	physical association, direct interaction

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005643 - nuclear pore GO:0006606 - protein import into nucleus GO:0006607 - NLS-bearing protein import into nucleus
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 823 Sc			1 1113
+	Sc
		541851 NSP1_YEAST (1-823): 3.8e-105: 344: 100.00		IMB3_YEAST (5-1065): 1.11e-110: 372: 17.51
+	Hs
		127345 P121A_HUMAN (17-622): 2.27e-19: 95.7: 11.11		IPO5_HUMAN (7-1105): 0: 563: 18.50
+	Sc
		691631 NUP2_YEAST (266-640): 3.09e-19: 94.9: 27.02		IMB4_YEAST (1-1113): 2.41e-177: 551: 100.00
+	Hs
		127197 NU214_HUMAN (3-480): 1.31e-13: 77.2: 13.84		IPO5_HUMAN (7-1105): 0: 563: 18.50
+	Sc
		595034 NUP1_YEAST (127-661): 8.67e-14: 77.6: 19.46		IMB4_YEAST (1-1113): 2.41e-177: 551: 100.00
+	Ce
		136533 O01576_CAEEL (59-822): 2.52e-41: 164: 14.53		Q9N5V3_CAEEL (6-1075): 2.67e-132: 431: 17.00
+	Hs
		740196 NUP62_HUMAN (301-823): 1.2e-48: 182: 17.11		CAND1_HUMAN (1-1112): 1.78e-93: 327: 11.03
+	Sc
		541927 NSP1_YEAST (1-823): 3.8e-105: 344: 100.00		IMB1_YEAST (6-696): 1.11e-36: 151: 13.31
+	Sc
		687906 NUP2_YEAST (266-640): 3.09e-19: 94.9: 27.02		IMB3_YEAST (5-1065): 1.11e-110: 372: 17.51
+	Sc
		595002 NUP1_YEAST (127-661): 8.67e-14: 77.6: 19.46		IMB3_YEAST (5-1065): 1.11e-110: 372: 17.51
+	Xl
		853823 Q91349_XENLA (291-823): 1.42e-55: 202: 21.25		IMB_XENLA (336-1075): 2.65e-46: 182: 11.11
+	Hs
		740152 NUP62_HUMAN (301-823): 1.2e-48: 182: 17.11		IMB1_HUMAN (336-1075): 4.67e-46: 181: 11.11
+	At
		1226226 NUP62_ARATH (100-821): 3.75e-43: 169: 13.46		IMB1_ARATH (216-1069): 1.51e-45: 179: 12.53
+	Hs
		727300 NU214_HUMAN (3-480): 1.31e-13: 77.2: 13.84		TNPO1_HUMAN (215-1056): 1.35e-74: 267: 12.02
+	Xl
		1137359 NU153_XENLA (75-663): 3.6e-15: 82.2: 10.27		Q5U4V0_XENLA (215-1056): 3.18e-70: 254: 12.37
+	Hs
		1060869 P121A_HUMAN (17-622): 2.27e-19: 95.7: 11.11		IMB1_HUMAN (336-1075): 4.67e-46: 181: 11.11
+	Hs
		727254 NU214_HUMAN (3-480): 1.31e-13: 77.2: 13.84		IMB1_HUMAN (336-1075): 4.67e-46: 181: 11.11
+	Sc
		691667 NUP2_YEAST (266-640): 3.09e-19: 94.9: 27.02		IMB1_YEAST (6-696): 1.11e-36: 151: 13.31
+	Sc
		595074 NUP1_YEAST (127-661): 8.67e-14: 77.6: 19.46		IMB1_YEAST (6-696): 1.11e-36: 151: 13.31
+	Ce
		248166 P91457_CAEEL (2-473): 5.44e-13: 75.3: 10.17		O62332_CAEEL (206-971): 8.25e-14: 78.3: 12.92