HitPredict

Interactor 1: CYC8 (P14922)
General transcriptional corepressor CYC8 (Glucose repression mediator protein CYC8)
Gene: CYC8

Interactor 2: MIG1 (P27705)
Regulatory protein MIG1 (Regulatory protein CAT4)
Gene: MIG1

Species: Saccharomyces cerevisiae S288C

Source: biogrid

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.83	0.60	0.708

Property	Details
Experiments	7705659, 7724528, 35028974, 15031717, 36854981
Identification Methods	two hybrid, pull down, affinity chromatography technology
Interaction Type	physical association, direct interaction

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0000122 - negative regulation of transcription by RNA polymerase II GO:0000978 - RNA polymerase II cis-regulatory region sequence-specific DNA binding GO:0005634 - nucleus GO:0045944 - positive regulation of transcription by RNA polymerase II
Homologous interactions	9

Homologous interactions

Color coding for hit scores

	1 966 Sc			1 504
+	Hs
		175185 OGT1_HUMAN (1-317): 7.62e-59: 221: 16.20		ZN436_HUMAN (82-309): 2e-64: 218: 7.81
+	Hs
		175055 OGT1_HUMAN (1-317): 7.62e-59: 221: 16.20		ZN397_HUMAN (137-224): 3.89e-24: 107: 10.64
+	Hs
		684760 STIP1_HUMAN (1-286): 6.54e-34: 140: 13.94		ZNF79_HUMAN (122-308): 2.93e-43: 161: 10.31
+	Hs
		174918 OGT1_HUMAN (1-317): 7.62e-59: 221: 16.20		ZKSC8_HUMAN (165-226): 4.31e-13: 73.7: 11.29
+	Hs
		174960 OGT1_HUMAN (1-317): 7.62e-59: 221: 16.20		ZN787_HUMAN (36-95): 2.91e-10: 63.9: 51.67
+	Hs
		174615 OGT1_HUMAN (1-317): 7.62e-59: 221: 16.20		WT1_HUMAN (36-90): 9.92e-09: 59.3: 48.28
+	Hs
		1160967 CTR9_HUMAN (6-720): 8.67e-46: 181: 11.05		KLF16_HUMAN (36-91): 9.07e-13: 70.1: 51.72
+	Hs
		183155 KDM6A_HUMAN (2-127): 3.25e-12: 73: 18.90		KLF16_HUMAN (36-91): 9.07e-13: 70.1: 51.72
+	Hs
		183172 KDM6A_HUMAN (2-127): 3.25e-12: 73: 18.90		KLF15_HUMAN (32-95): 6.47e-11: 66.2: 50.00