HitPredict

Interactor 1: PLAK (P14923)
Junction plakoglobin (Catenin gamma) (Desmoplakin III) (Desmoplakin-3)
Gene: JUP

Interactor 2: ARNT (P27540)
Aryl hydrocarbon receptor nuclear translocator (ARNT protein) (Class E basic helix-loop-helix protein 2) (bHLHe2) (Dioxin receptor, nuclear translocator) (Hypoxia-inducible factor 1-beta) (HIF-1-beta) (HIF1-beta)
Gene: ARNT

Species: Homo sapiens

Source: biogrid

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.60	0.479

Property	Details
Experiments	33591636
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005634 - nucleus GO:0005737 - cytoplasm GO:0042803 - protein homodimerization activity GO:0045944 - positive regulation of transcription by RNA polymerase II
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 745 Hs			1 789
+	Hs
		649045 CTNB1_HUMAN (1-731): 1.58e-173: 519: 67.38		ARNT_HUMAN (1-789): 0: 649: 100.00
+	Hs
		542426 PLAK_HUMAN (1-745): 0: 551: 100.00		EPAS1_HUMAN (76-771): 3.47e-132: 415: 16.85
+	Hs
		542343 PLAK_HUMAN (1-745): 0: 551: 100.00		HIF1A_HUMAN (82-787): 5.9e-129: 406: 17.48
+	Hs
		717306 CTNB1_HUMAN (1-731): 1.58e-173: 519: 67.38		EPAS1_HUMAN (76-771): 3.47e-132: 415: 16.85
+	Hs
		717124 CTNB1_HUMAN (1-731): 1.58e-173: 519: 67.38		HIF1A_HUMAN (82-787): 5.9e-129: 406: 17.48
+	Hs
		717108 CTNB1_HUMAN (1-731): 1.58e-173: 519: 67.38		NCOA2_HUMAN (67-741): 1.06e-106: 359: 14.84
+	Hs
		131380 IMA4_HUMAN (228-670): 5.34e-64: 224: 15.79		ARNT_HUMAN (1-789): 0: 649: 100.00
+	Hs
		649071 IMA5_HUMAN (231-685): 6.58e-61: 215: 15.06		ARNT_HUMAN (1-789): 0: 649: 100.00
+	Hs
		716825 CTNB1_HUMAN (1-731): 1.58e-173: 519: 67.38		AHR_HUMAN (64-767): 5.39e-93: 311: 14.89
+	Hs
		238633 IMA7_HUMAN (262-685): 3.97e-45: 172: 13.86		ARNT_HUMAN (1-789): 0: 649: 100.00
+	Hs
		168619 IMA6_HUMAN (273-659): 3.11e-41: 160: 13.95		ARNT_HUMAN (1-789): 0: 649: 100.00
+	Hs
		1132863 ODAD2_HUMAN (136-663): 2.3e-108: 356: 19.34		NPAS1_HUMAN (49-640): 1.14e-101: 327: 15.82
+	Hs
		131501 IMA4_HUMAN (228-670): 5.34e-64: 224: 15.79		EPAS1_HUMAN (76-771): 3.47e-132: 415: 16.85
+	Hs
		134908 IMA3_HUMAN (228-670): 2.7e-65: 227: 16.01		HIF1A_HUMAN (82-787): 5.9e-129: 406: 17.48
+	Hs
		131446 IMA4_HUMAN (228-670): 5.34e-64: 224: 15.79		HIF1A_HUMAN (82-787): 5.9e-129: 406: 17.48
+	Hs
		853691 IMA5_HUMAN (231-685): 6.58e-61: 215: 15.06		EPAS1_HUMAN (76-771): 3.47e-132: 415: 16.85
+	Hs
		853610 IMA5_HUMAN (231-685): 6.58e-61: 215: 15.06		HIF1A_HUMAN (82-787): 5.9e-129: 406: 17.48
+	Hs
		238729 IMA7_HUMAN (262-685): 3.97e-45: 172: 13.86		EPAS1_HUMAN (76-771): 3.47e-132: 415: 16.85
+	Hs
		238688 IMA7_HUMAN (262-685): 3.97e-45: 172: 13.86		HIF1A_HUMAN (82-787): 5.9e-129: 406: 17.48
+	Dm
		283969 O76521_DROME (229-679): 6.52e-67: 232: 15.42		PER_DROME (173-458): 5.28e-12: 72: 26.80