Protein: BTBD1
BTB/POZ domain-containing protein 1 (Hepatitis C virus NS5A-transactivated protein 8) (HCV NS5A-transactivated protein 8)

Gene: BTBD1
Organism: Homo sapiens
Interactions: 117
UniProt ID: Q9H0C5

Gene Ontology (top 5):
GO:0000932 - P-body
GO:0005654 - nucleoplasm
GO:0005829 - cytosol
GO:0007517 - muscle organ development
GO:0016567 - protein ubiquitination

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

1114255

CUL3
Cullin-3

14

20

Small-scale

0.981

High

1416604

BTBD2
BTB/POZ domain-containing protein 2

2

19

High-throughput

0.811

High

1429752

BTBD1
BTB/POZ domain-containing protein 1

2

19

High-throughput

0.783

High

1272558

CSN6
COP9 signalosome complex subunit 6

5

13

High-throughput

0.722

High

1370364

CSN5
COP9 signalosome complex subunit 5

5

13

High-throughput

0.718

High

1429769

CSN3
COP9 signalosome complex subunit 3

4

20

High-throughput

0.694

High

1371858

CUL5
Cullin-5

1

20

High-throughput

0.691

High

958712

CSN2
COP9 signalosome complex subunit 2

4

20

High-throughput

0.691

High

1429764

CSN7A
COP9 signalosome complex subunit 7a

3

7

High-throughput

0.675

High

957510

UBC12
NEDD8-conjugating enzyme Ubc12

3

18

High-throughput

0.667

High

1046418

UBXN1
UBX domain-containing protein 1

3

11

High-throughput

0.667

High

1413195

CSN4
COP9 signalosome complex subunit 4

3

5

High-throughput

0.667

High

1429753

EPN3
Epsin-3

3

1

High-throughput

0.667

High

1429762

TLS1
Splicing factor C9orf78

3

1

High-throughput

0.667

High

1392899

NTAQ1
Protein N-terminal glutamine amidohydrolase

3

6

High-throughput

0.665

High

1094416

CSN1
COP9 signalosome complex subunit 1

3

19

High-throughput

0.662

High

1104668

IKZF1
DNA-binding protein Ikaros

3

2

High-throughput

0.662

High

542211

TOP1
DNA topoisomerase 1

2

2

Small-scale

0.633

High

1336472

PNMA1
Paraneoplastic antigen Ma1

4

2

High-throughput

0.630

High

885892

KC1E
Casein kinase I isoform epsilon

2

6

High-throughput

0.628

High

900503

FXR2
RNA-binding protein FXR2

2

5

High-throughput

0.628

High

1406127

CSN8
COP9 signalosome complex subunit 8

2

5

High-throughput

0.628

High

1429755

CSN7B
COP9 signalosome complex subunit 7b

2

7

High-throughput

0.628

High

1429766

PP13
Galactoside-binding soluble lectin 13

2

1

High-throughput

0.628

High

1329493

OTU6B
Deubiquitinase OTUD6B

3

3

High-throughput

0.609

High

1429768

OSGI1
Oxidative stress-induced growth inhibitor 1

3

1

High-throughput

0.609

High

1005080

RNF4
E3 ubiquitin-protein ligase RNF4

2

3

High-throughput

0.606

High

1157421

PSMD5
26S proteasome non-ATPase regulatory subunit 5

2

1

High-throughput

0.606

High

1348492

LNX1
E3 ubiquitin-protein ligase LNX

2

8

High-throughput

0.606

High

1335317

FA98A
Protein FAM98A

3

1

High-throughput

0.604

High

351354

SYF2
Pre-mRNA-splicing factor SYF2

2

0

High-throughput

0.602

High

874061

TPC10
Trafficking protein particle complex subunit 10

2

0

High-throughput

0.602

High

1292080

SPA24
Spermatogenesis-associated protein 24

2

0

High-throughput

0.602

High

1293531

CIR1
Corepressor interacting with RBPJ 1

2

0

High-throughput

0.602

High

1400439

TPPC9
Trafficking protein particle complex subunit 9

2

0

High-throughput

0.602

High

1429770

TPPC4
Trafficking protein particle complex subunit 4

2

0

High-throughput

0.602

High

1326551

CARME
Carnosine N-methyltransferase

2

1

High-throughput

0.601

High

611753

BMP7
Bone morphogenetic protein 7

2

1

High-throughput

0.574

High

1332372

IQUB
IQ motif and ubiquitin-like domain-containing protein

2

1

High-throughput

0.574

High

1366776

NECT2
Nectin-2

2

9

High-throughput

0.574

High

1371188

GLMN
Glomulin

2

1

High-throughput

0.574

High

1429756

LRC4C
Leucine-rich repeat-containing protein 4C

2

5

High-throughput

0.574

High

1103522

MPP3
MAGUK p55 subfamily member 3

2

3

High-throughput

0.553

High

1057112

FMOD
Fibromodulin

1

2

Small-scale

0.553

High

279489

TULP3
Tubby-related protein 3

1

1

High-throughput

0.541

High

1361835

RSPH1
Radial spoke head 1 homolog

1

1

High-throughput

0.541

High

405541

KITH
Thymidine kinase, cytosolic

1

2

High-throughput

0.536

High

984270

GBB2
Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-2

1

2

High-throughput

0.536

High

1109567

4EBP1
Eukaryotic translation initiation factor 4E-binding protein 1

1

1

High-throughput

0.536

High

1360283

CSN9
COP9 signalosome complex subunit 9

1

2

High-throughput

0.536

High

1394240

BOD1
Biorientation of chromosomes in cell division protein 1

1

3

High-throughput

0.536

High

1429758

ARHG4
Rho guanine nucleotide exchange factor 4

1

6

High-throughput

0.536

High

1429765

UBP25
Ubiquitin carboxyl-terminal hydrolase 25

1

14

High-throughput

0.536

High

461916

HS90A
Heat shock protein HSP 90-alpha

1

16

High-throughput

0.534

High

615238

IL1RA
Interleukin-1 receptor antagonist protein

1

1

High-throughput

0.515

High

947845

TPPP2
Tubulin polymerization-promoting protein family member 2

1

1

High-throughput

0.515

High

728426

AKT1
RAC-alpha serine/threonine-protein kinase

1

8

High-throughput

0.515

High

1096218

TADBP
TAR DNA-binding protein 43

1

5

High-throughput

0.515

High

369087

ASSY
Argininosuccinate synthase

1

0

High-throughput

0.513

High

486615

TACD2
Tumor-associated calcium signal transducer 2

1

0

High-throughput

0.513

High

986705

PPIA
Peptidyl-prolyl cis-trans isomerase A

1

0

High-throughput

0.513

High

1307847

TPPC5
Trafficking protein particle complex subunit 5

1

0

High-throughput

0.513

High

1338835

FLCN
Folliculin

1

0

High-throughput

0.513

High

1367902

THRSP
Thyroid hormone-inducible hepatic protein

1

0

High-throughput

0.513

High

1429757

SHLB2
Endophilin-B2

1

0

High-throughput

0.513

High

1429761

PLAT2
Phospholipase A and acyltransferase 2

1

0

High-throughput

0.513

High

508593

UBC
Polyubiquitin-C [Cleaved into: Ubiquitin]

1

13

High-throughput

0.501

High

249196

DSCAM
Cell adhesion molecule DSCAM

1

1

High-throughput

0.494

High

244900

LZTS3
Leucine zipper putative tumor suppressor 3

1

8

High-throughput

0.489

High

415149

AMYP
Pancreatic alpha-amylase

1

2

High-throughput

0.489

High

458022

TRY2
Trypsin-2

1

2

High-throughput

0.489

High

479079

CEL3A
Chymotrypsin-like elastase family member 3A

1

3

High-throughput

0.489

High

539902

RALB
Ras-related protein Ral-B

1

3

High-throughput

0.489

High

598275

CL3L1
C-C motif chemokine 3-like 1

1

2

High-throughput

0.489

High

1150483

NHRF2
Na(+)/H(+) exchange regulatory cofactor NHE-RF2

1

10

High-throughput

0.489

High

1293600

HOGA1
4-hydroxy-2-oxoglutarate aldolase, mitochondrial

1

1

High-throughput

0.489

High

1322355

ZN444
Zinc finger protein 444

1

11

High-throughput

0.489

High

1328120

TTC9C
Tetratricopeptide repeat protein 9C

1

4

High-throughput

0.489

High

1383427

CC74A
Coiled-coil domain-containing protein 74A

1

1

High-throughput

0.489

High

1394346

ZN414
Zinc finger protein 414

1

4

High-throughput

0.489

High

1397732

CC74B
Coiled-coil domain-containing protein 74B

1

1

High-throughput

0.489

High

1397743

MAGBA
Melanoma-associated antigen B10

1

1

High-throughput

0.489

High

1398302

ROBO3
Roundabout homolog 3

1

5

High-throughput

0.489

High

1404984

GA2L1
GAS2-like protein 1

1

3

High-throughput

0.489

High

1409939

DDX50
ATP-dependent RNA helicase DDX50

1

1

High-throughput

0.489

High

1429754

TAOK3
Serine/threonine-protein kinase TAO3

1

8

High-throughput

0.489

High

983968

RBX1
E3 ubiquitin-protein ligase RBX1

1

11

Small-scale

0.479

High

1396700

LLR1
Leucine-rich repeat protein 1

1

3

Small-scale

0.479

High

1429771

ARI1
E3 ubiquitin-protein ligase ARIH1

1

17

High-throughput

0.479

High

880961

MTR1B
Melatonin receptor type 1B

1

4

High-throughput

0.464

High

1056962

FMR1
Fragile X messenger ribonucleoprotein 1

1

5

High-throughput

0.457

High

1059956

KHDR1
KH domain-containing, RNA-binding, signal transduction-associated protein 1

1

1

High-throughput

0.457

High

1429759

DISC1
Disrupted in schizophrenia 1 protein

1

5

High-throughput

0.457

High

1400134

SYGP1
Ras/Rap GTPase-activating protein SynGAP

1

6

High-throughput

0.445

High

1429767

RABX5
Rab5 GDP/GTP exchange factor

1

3

High-throughput

0.445

High

947046

DSCR9
Down syndrome critical region protein 9

1

1

High-throughput

0.417

High

379776

IGHA2
Immunoglobulin heavy constant alpha 2

1

7

High-throughput

0.407

High

517261

AMY1B
Alpha-amylase 1B

1

1

High-throughput

0.407

High

1202119

HS904
Putative heat shock protein HSP 90-alpha A4

1

18

High-throughput

0.407

High

156164

TRAD1
TRAF-type zinc finger domain-containing protein 1

2

0

High-throughput

0.328

High

220714

DENR
Density-regulated protein

2

0

High-throughput

0.328

High

581423

CBPN
Carboxypeptidase N catalytic chain

2

0

High-throughput

0.328

High

1351646

TCP1L
T-complex protein 10A homolog 1

2

0

High-throughput

0.328

High

1429760

C42S1
CDC42 small effector protein 1

2

0

High-throughput

0.328

High

1420840

SEM4C
Semaphorin-4C

2

0

High-throughput

0.313

High

518442

PYY
Peptide YY

1

0

High-throughput

0.279

Low

569596

CATE
Cathepsin E

1

0

High-throughput

0.279

Low

702413

CYTD
Cystatin-D

1

0

High-throughput

0.279

Low

1127335

WFDC2
WAP four-disulfide core domain protein 2

1

0

High-throughput

0.279

Low

1379839

LEAP2
Liver-expressed antimicrobial peptide 2

1

0

High-throughput

0.279

Low

1412330

GDAH
Guanidino acid hydrolase, mitochondrial

1

0

High-throughput

0.279

Low

1419751

EVG1
UPF0193 protein EVG1

1

0

High-throughput

0.279

Low

1429763

GSKIP
GSK3B-interacting protein

1

0

High-throughput

0.279

Low

939020

UCP2
Dicarboxylate carrier SLC25A8

1

0

High-throughput

0.269

Low

660298

BDNF
Neurotrophic factor BDNF precursor form

1

0

High-throughput

0.268

Low

1249199

LMBRL
Protein LMBR1L

1

0

High-throughput

0.249

Low


Service provided by Combinatics, Japan

Last updated: 11Aug2025