HitPredict

Interactor 1: PLAK (P14923)
Junction plakoglobin (Catenin gamma) (Desmoplakin III) (Desmoplakin-3)
Gene: JUP

Interactor 2: RHOJ (Q9H4E5)
Rho-related GTP-binding protein RhoJ (Ras-like protein family member 7B) (Tc10-like GTP-binding protein)
Gene: RHOJ

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	1.00	0.618

Property	Details
Experiments	31871319
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	Arm~Ras
Common GO terms	GO:0005886 - plasma membrane GO:0070062 - extracellular exosome
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 745 Hs			1 214
+	Hs
		542255 PLAK_HUMAN (1-745): 0: 551: 100.00		CDC42_HUMAN (20-204): 2.24e-92: 270: 63.78
+	Hs
		542271 PLAK_HUMAN (1-745): 0: 551: 100.00		RAC1_HUMAN (22-214): 4.7e-82: 243: 57.51
+	Hs
		542258 PLAK_HUMAN (1-745): 0: 551: 100.00		RHOA_HUMAN (23-214): 1.09e-80: 240: 47.92
+	Hs
		716931 CTNB1_HUMAN (1-731): 1.58e-173: 519: 67.38		CDC42_HUMAN (20-204): 2.24e-92: 270: 63.78
+	Hs
		436141 PLAK_HUMAN (1-745): 0: 551: 100.00		RHOC_HUMAN (23-214): 6.63e-79: 236: 48.44
+	Hs
		542164 PLAK_HUMAN (1-745): 0: 551: 100.00		RAC2_HUMAN (22-214): 1.98e-78: 235: 57.51
+	Hs
		542276 PLAK_HUMAN (1-745): 0: 551: 100.00		RHOG_HUMAN (20-214): 1.44e-78: 235: 50.26
+	Hs
		542173 PLAK_HUMAN (1-745): 0: 551: 100.00		RHOQ_HUMAN (22-213): 5.09e-77: 231: 79.49
+	Hs
		542254 PLAK_HUMAN (1-745): 0: 551: 100.00		RAC3_HUMAN (22-195): 2.97e-77: 231: 62.64
+	Hs
		542268 PLAK_HUMAN (1-745): 0: 551: 100.00		RHOB_HUMAN (23-214): 1.69e-76: 230: 48.44
+	Hs
		717346 CTNB1_HUMAN (1-731): 1.58e-173: 519: 67.38		RHOJ_HUMAN (1-214): 2.19e-84: 250: 100.00
+	Hs
		716971 CTNB1_HUMAN (1-731): 1.58e-173: 519: 67.38		RAC1_HUMAN (22-214): 4.7e-82: 243: 57.51
+	Mm
		925786 CTNB1_MOUSE (1-731): 2.79e-173: 518: 67.38		RAC1_MOUSE (22-214): 4.7e-82: 243: 57.51
+	Hs
		716935 CTNB1_HUMAN (1-731): 1.58e-173: 519: 67.38		RHOA_HUMAN (23-214): 1.09e-80: 240: 47.92
+	Hs
		545229 CTNB1_HUMAN (1-731): 1.58e-173: 519: 67.38		RAC2_HUMAN (22-214): 1.98e-78: 235: 57.51
+	Hs
		716991 CTNB1_HUMAN (1-731): 1.58e-173: 519: 67.38		RHOG_HUMAN (20-214): 1.44e-78: 235: 50.26
+	Hs
		564428 CTNB1_HUMAN (1-731): 1.58e-173: 519: 67.38		RHOQ_HUMAN (22-213): 5.09e-77: 231: 79.49
+	Hs
		716929 CTNB1_HUMAN (1-731): 1.58e-173: 519: 67.38		RAC3_HUMAN (22-195): 2.97e-77: 231: 62.64
+	Hs
		716955 CTNB1_HUMAN (1-731): 1.58e-173: 519: 67.38		RHOB_HUMAN (23-214): 1.69e-76: 230: 48.44
+	Mm
		677654 CTND1_MOUSE (207-730): 3.06e-94: 315: 16.42		RHOA_MOUSE (23-214): 3.52e-81: 242: 48.44