HitPredict

Interactor 1: BRAF (P15056)
Serine/threonine-protein kinase B-raf (EC 2.7.11.1) (Proto-oncogene B-Raf) (p94) (v-Raf murine sarcoma viral oncogene homolog B1)
Gene: BRAF

Interactor 2: KPCE (Q02156)
Protein kinase C epsilon type (EC 2.7.11.13) (nPKC-epsilon)
Gene: PRKCE

Species: Homo sapiens

Source: mint

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.60 1.00 0.776

The method score is based on:

Property Details
Experiments 16810323, 21625473
Identification Methods affinity chromatography technology, anti bait coimmunoprecipitation
Interaction Type physical association

The annotation score is based on:

Property Details
Interacting Pfam domains C1_1~C1_1, C1_1~C2, C1_1~Pkinase, C1_1~PK_Tyr_Ser-Thr, PK_Tyr_Ser-Thr~Pkinase, C1_1~RBD
Common GO terms GO:0000165 - MAPK cascade
GO:0004672 - protein kinase activity
GO:0004674 - protein serine/threonine kinase activity
GO:0005524 - ATP binding
GO:0005634 - nucleus
and 6 others

more...
Homologous interactions 12

Homologous interactions

Color coding for hit scores

1 766
Hs

1 737
+ Hs
+ Mm
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Service provided by Combinatics, Japan

Last updated: 15 Jul 2024