Protein: TACC1
Transforming acidic coiled-coil-containing protein 1 (Gastric cancer antigen Ga55) (Taxin-1)

Gene: TACC1
Organism: Homo sapiens
Interactions: 169
UniProt ID: O75410

Gene Ontology (top 5):
GO:0000226 - microtubule cytoskeleton organization
GO:0003713 - transcription coactivator activity
GO:0005634 - nucleus
GO:0005737 - cytoplasm
GO:0005813 - centrosome

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

280978

TACC2
Transforming acidic coiled-coil-containing protein 2

3

16

High-throughput

0.861

High

281120

FBW1A
F-box/WD repeat-containing protein 1A

7

13

High-throughput

0.752

High

281110

VAPA
Vesicle-associated membrane protein-associated protein A

5

6

High-throughput

0.720

High

280977

VAPB
Vesicle-associated membrane protein-associated protein B/C

5

6

High-throughput

0.716

High

281042

CKAP5
Cytoskeleton-associated protein 5

4

11

Small-scale

0.713

High

281098

SH24A
SH2 domain-containing protein 4A

4

9

High-throughput

0.698

High

281115

FBW1B
F-box/WD repeat-containing protein 11

4

11

High-throughput

0.694

High

281121

MEMO1
Protein MEMO1

4

0

High-throughput

0.673

High

281097

RNF41
E3 ubiquitin-protein ligase NRDP1

3

6

Small-scale

0.671

High

280985

RPN2
Dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit 2

3

1

High-throughput

0.667

High

281011

HD
Huntingtin

3

4

High-throughput

0.664

High

281114

LSM7
U6 snRNA-associated Sm-like protein LSm7

2

5

Small-scale

0.654

High

169852

AURKA
Aurora kinase A

3

11

Small-scale

0.653

High

281026

RUXG
Small nuclear ribonucleoprotein G

2

5

Small-scale

0.647

High

215763

P52K
52 kDa repressor of the inhibitor of the protein kinase

3

0

High-throughput

0.646

High

281038

STX5
Syntaxin-5

2

5

High-throughput

0.644

High

281079

DTBP1
Dysbindin

3

0

High-throughput

0.638

High

281020

STAT2
Signal transducer and activator of transcription 2

2

1

High-throughput

0.628

High

281069

POC1B
POC1 centriolar protein homolog B

2

7

High-throughput

0.628

High

280984

RPN1
Dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit 1

2

1

High-throughput

0.611

High

281047

MARE1
Microtubule-associated protein RP/EB family member 1

2

6

High-throughput

0.611

High

280992

THA
Thyroid hormone receptor alpha

2

13

High-throughput

0.606

High

281048

ZFHX3
Zinc finger homeobox protein 3

2

2

High-throughput

0.606

High

281075

XPF
DNA repair endonuclease XPF

2

1

High-throughput

0.606

High

281067

TDRD7
Tudor domain-containing protein 7

1

3

Small-scale

0.602

High

281124

SKAP
Small kinetochore-associated protein

2

0

High-throughput

0.602

High

51383

FSD2
Fibronectin type III and SPRY domain-containing protein 2

2

13

High-throughput

0.601

High

280981

RASK
GTPase KRas

2

11

High-throughput

0.584

High

281022

SC61B
Protein transport protein Sec61 subunit beta

2

2

High-throughput

0.584

High

281027

RB11A
Ras-related protein Rab-11A

2

2

High-throughput

0.584

High

281084

ZNF48
Zinc finger protein 48

2

0

High-throughput

0.580

High

281119

FA50B
Protein FAM50B

2

0

High-throughput

0.580

High

261745

PFD1
Prefoldin subunit 1

2

0

High-throughput

0.576

High

96822

E9PBC6
Transforming acidic coiled-coil containing protein 2

1

15

High-throughput

0.575

High

280979

YETS4
YEATS domain-containing protein 4

1

1

Small-scale

0.573

High

144211

ACACB
Acetyl-CoA carboxylase 2

1

5

High-throughput

0.536

High

281009

OST48
Dolichyl-diphosphooligosaccharide--protein glycosyltransferase 48 kDa subunit

1

1

High-throughput

0.536

High

281029

TBA1B
Tubulin alpha-1B chain

1

15

High-throughput

0.536

High

281030

TBB4B
Tubulin beta-4B chain

1

5

High-throughput

0.536

High

281044

BRD3
Bromodomain-containing protein 3

1

14

High-throughput

0.536

High

281068

PMFBP
Polyamine-modulated factor 1-binding protein 1

1

11

High-throughput

0.536

High

281070

RBCC1
RB1-inducible coiled-coil protein 1

1

17

High-throughput

0.536

High

281089

LYST
Lysosomal-trafficking regulator

1

12

High-throughput

0.536

High

281113

BI2L1
BAR/IMD domain-containing adapter protein 2-like 1

1

6

High-throughput

0.536

High

281000

RAB4A
Ras-related protein Rab-4A

2

3

High-throughput

0.533

High

281117

ALK
ALK tyrosine kinase receptor

2

19

High-throughput

0.533

High

281080

AURKB
Aurora kinase B

1

12

Small-scale

0.515

High

281055

TPGS1
Tubulin polyglutamylase complex subunit 1

1

0

High-throughput

0.513

High

246341

KDM1A
Lysine-specific histone demethylase 1A

1

8

High-throughput

0.508

High

281074

KAT2A
Histone acetyltransferase KAT2A

1

16

Small-scale

0.501

High

280990

ROS1
Proto-oncogene tyrosine-protein kinase ROS

1

19

High-throughput

0.500

High

281063

KT222
Keratin-like protein KRT222

1

6

High-throughput

0.489

High

281091

KXDL1
KxDL motif-containing protein 1

1

2

High-throughput

0.489

High

281109

ITSN2
Intersectin-2

1

5

High-throughput

0.481

High

126400

RHOD
Rho-related GTP-binding protein RhoD

1

20

High-throughput

0.479

High

173794

AT2A1
Sarcoplasmic/endoplasmic reticulum calcium ATPase 1

1

3

High-throughput

0.479

High

225884

STX6
Syntaxin-6

1

2

High-throughput

0.479

High

278786

PEX14
Peroxisomal membrane protein PEX14

1

1

High-throughput

0.479

High

280975

NU155
Nuclear pore complex protein Nup155

1

2

High-throughput

0.479

High

280980

RASN
GTPase NRas

1

14

High-throughput

0.479

High

280982

ESR1
Estrogen receptor

1

20

Small-scale

0.479

High

280983

ERBB2
Receptor tyrosine-protein kinase erbB-2

1

20

High-throughput

0.479

High

280986

INSR
Insulin receptor

1

20

High-throughput

0.479

High

280988

IGF1R
Insulin-like growth factor 1 receptor

1

20

High-throughput

0.479

High

280989

RHOC
Rho-related GTP-binding protein RhoC

1

20

High-throughput

0.479

High

280993

FGFR1
Fibroblast growth factor receptor 1

1

14

High-throughput

0.479

High

280994

CP2C9
Cytochrome P450 2C9

1

1

High-throughput

0.479

High

280996

RAC2
Ras-related C3 botulinum toxin substrate 2

1

20

High-throughput

0.479

High

280997

CXA1
Gap junction alpha-1 protein

1

2

High-throughput

0.479

High

280998

PTN1
Tyrosine-protein phosphatase non-receptor type 1

1

3

High-throughput

0.479

High

280999

RAB3B
Ras-related protein Rab-3B

1

6

High-throughput

0.479

High

281001

RAB5A
Ras-related protein Rab-5A

1

5

High-throughput

0.479

High

281003

CALX
Calnexin

1

7

High-throughput

0.479

High

281004

TMOD1
Tropomodulin-1

1

1

High-throughput

0.479

High

281006

MARCS
Myristoylated alanine-rich C-kinase substrate

1

7

High-throughput

0.479

High

281007

BASI
Basigin

1

4

High-throughput

0.479

High

281008

VGFR3
Vascular endothelial growth factor receptor 3

1

12

High-throughput

0.479

High

281010

LAP2B
Lamina-associated polypeptide 2, isoforms beta/gamma

1

2

High-throughput

0.479

High

281012

SSRA
Translocon-associated protein subunit alpha

1

3

High-throughput

0.479

High

281013

LMAN1
Protein ERGIC-53

1

1

High-throughput

0.479

High

281014

EMD
Emerin

1

2

High-throughput

0.479

High

281016

RAB7A
Ras-related protein Rab-7a

1

9

High-throughput

0.479

High

281017

RAB9A
Ras-related protein Rab-9A

1

10

High-throughput

0.479

High

281018

BAP31
B-cell receptor-associated protein 31

1

2

High-throughput

0.479

High

281019

RND2
Rho-related GTP-binding protein RhoN

1

20

High-throughput

0.479

High

281023

RAC3
Ras-related C3 botulinum toxin substrate 3

1

20

High-throughput

0.479

High

281024

CDC42
Cell division control protein 42 homolog

1

20

High-throughput

0.479

High

281025

RHOA
Transforming protein RhoA

1

20

High-throughput

0.479

High

281028

PPIA
Peptidyl-prolyl cis-trans isomerase A

1

7

High-throughput

0.479

High

281031

CXAR
Coxsackievirus and adenovirus receptor

1

3

High-throughput

0.479

High

281032

RHOG
Rho-related GTP-binding protein RhoG

1

20

High-throughput

0.479

High

281035

TYRO3
Tyrosine-protein kinase receptor TYRO3

1

20

High-throughput

0.479

High

281036

CKAP4
Cytoskeleton-associated protein 4

1

11

High-throughput

0.479

High

281037

STX4
Syntaxin-4

1

4

High-throughput

0.479

High

281041

CUL3
Cullin-3

1

11

High-throughput

0.479

High

281043

FKBP8
Peptidyl-prolyl cis-trans isomerase FKBP8

1

3

High-throughput

0.479

High

281045

RAB35
Ras-related protein Rab-35

1

8

High-throughput

0.479

High

281049

NTRK3
NT-3 growth factor receptor

1

17

High-throughput

0.479

High

281053

SYNE3
Nesprin-3

1

9

High-throughput

0.479

High

281054

TRI67
Tripartite motif-containing protein 67

1

14

High-throughput

0.479

High

281057

SYVN1
E3 ubiquitin-protein ligase synoviolin

1

8

High-throughput

0.479

High

281058

NAA40
N-alpha-acetyltransferase 40

1

3

High-throughput

0.479

High

281059

DYR2
Dihydrofolate reductase 2, mitochondrial

1

2

High-throughput

0.479

High

281061

MIRO2
Mitochondrial Rho GTPase 2

1

20

High-throughput

0.479

High

281065

DHB11
Estradiol 17-beta-dehydrogenase 11

1

4

High-throughput

0.479

High

281066

PDZD8
PDZ domain-containing protein 8

1

1

High-throughput

0.479

High

281072

AKAP1
A-kinase anchor protein 1, mitochondrial

1

3

High-throughput

0.479

High

281073

ESR2
Estrogen receptor beta

1

20

High-throughput

0.479

High

281076

ERGI1
Endoplasmic reticulum-Golgi intermediate compartment protein 1

1

2

High-throughput

0.479

High

281078

LRC59
Leucine-rich repeat-containing protein 59

1

2

High-throughput

0.479

High

281082

DNJC1
DnaJ homolog subfamily C member 1

1

6

High-throughput

0.479

High

281086

ERGI2
Endoplasmic reticulum-Golgi intermediate compartment protein 2

1

2

High-throughput

0.479

High

281087

RMD3
Regulator of microtubule dynamics protein 3

1

1

High-throughput

0.479

High

281088

SEC62
Translocation protein SEC62

1

2

High-throughput

0.479

High

281090

BARD1
BRCA1-associated RING domain protein 1

1

14

Small-scale

0.479

High

281092

ESYT1
Extended synaptotagmin-1

1

4

High-throughput

0.479

High

281093

DERL1
Derlin-1

1

2

High-throughput

0.479

High

281094

LNP
Endoplasmic reticulum junction formation protein lunapark

1

3

High-throughput

0.479

High

281099

TMT1A
Thiol S-methyltransferase TMT1A

1

1

High-throughput

0.479

High

281100

PXMP2
Peroxisomal membrane protein 2

1

1

High-throughput

0.479

High

281101

ST7
Suppressor of tumorigenicity 7 protein

1

1

High-throughput

0.479

High

281102

TOM22
Mitochondrial import receptor subunit TOM22 homolog

1

1

High-throughput

0.479

High

281104

EXD2
Exonuclease 3'-5' domain-containing protein 2

1

1

High-throughput

0.479

High

281105

OCAD1
OCIA domain-containing protein 1

1

1

High-throughput

0.479

High

281108

MTCH1
Mitochondrial carrier homolog 1

1

8

High-throughput

0.479

High

281112

ZRAN1
Ubiquitin thioesterase ZRANB1

1

10

High-throughput

0.479

High

281116

CLC4E
C-type lectin domain family 4 member E

1

1

High-throughput

0.479

High

281118

MARE3
Microtubule-associated protein RP/EB family member 3

1

6

High-throughput

0.479

High

281125

MTCH2
Mitochondrial carrier homolog 2

1

7

High-throughput

0.479

High

166827

MGST3
Glutathione S-transferase 3, mitochondrial

1

0

High-throughput

0.458

High

280976

ZFPL1
Zinc finger protein-like 1

1

0

High-throughput

0.458

High

281060

TEX2
Testis-expressed protein 2

1

0

High-throughput

0.458

High

281085

PANX1
Pannexin-1

1

0

High-throughput

0.458

High

281103

OTULL
Inactive ubiquitin thioesterase OTULINL

1

0

High-throughput

0.458

High

281106

MARH5
E3 ubiquitin-protein ligase MARCHF5

1

0

High-throughput

0.458

High

281107

ELOV5
Very long chain fatty acid elongase 5

1

0

High-throughput

0.458

High

281111

B3GA1
Galactosylgalactosylxylosylprotein 3-beta-glucuronosyltransferase 1

1

0

High-throughput

0.458

High

281122

FIS1
Mitochondrial fission 1 protein

1

0

High-throughput

0.458

High

281123

PTH2
Peptidyl-tRNA hydrolase 2, mitochondrial

1

0

High-throughput

0.458

High

281056

TBA1A
Tubulin alpha-1A chain

1

15

High-throughput

0.445

High

104958

APRIO
Alternative prion protein

1

6

High-throughput

0.437

High

179586

MUSK
Muscle, skeletal receptor tyrosine-protein kinase

1

20

High-throughput

0.437

High

189348

STX7
Syntaxin-7

1

4

High-throughput

0.437

High

280987

RET
Proto-oncogene tyrosine-protein kinase receptor Ret

1

20

High-throughput

0.437

High

280995

INSRR
Insulin receptor-related protein

1

20

High-throughput

0.437

High

281002

ERBB3
Receptor tyrosine-protein kinase erbB-3

1

20

High-throughput

0.437

High

281005

EPHA8
Ephrin type-A receptor 8

1

13

High-throughput

0.437

High

281015

RAB5C
Ras-related protein Rab-5C

1

6

High-throughput

0.437

High

281021

RAB25
Ras-related protein Rab-25

1

2

High-throughput

0.437

High

281033

REEP5
Receptor expression-enhancing protein 5

1

2

High-throughput

0.437

High

281034

ROR2
Tyrosine-protein kinase transmembrane receptor ROR2

1

16

High-throughput

0.437

High

281046

TOM20
Mitochondrial import receptor subunit TOM20 homolog

1

1

High-throughput

0.437

High

281050

DCA15
DDB1- and CUL4-associated factor 15

1

2

High-throughput

0.437

High

281051

RNF43
E3 ubiquitin-protein ligase RNF43

1

4

High-throughput

0.437

High

281052

SOSD1
Sclerostin domain-containing protein 1

1

2

Small-scale

0.437

High

281062

CXD3
Gap junction delta-3 protein

1

2

High-throughput

0.437

High

281064

ARL10
ADP-ribosylation factor-like protein 10

1

7

High-throughput

0.437

High

281071

DYH7
Dynein axonemal heavy chain 7

1

2

High-throughput

0.437

High

281095

DJC25
DnaJ homolog subfamily C member 25

1

4

High-throughput

0.437

High

281096

3BHS7
3 beta-hydroxysteroid dehydrogenase type 7

1

1

High-throughput

0.437

High

281083

MF14A
Hippocampus abundant transcript 1 protein

1

0

High-throughput

0.426

High

3428

A0A0S2Z507
Beta-transducin repeat containing isoform 3

1

14

High-throughput

0.417

High

85135

B7Z3H4
Beta-transducin repeat containing E3 ubiquitin protein ligase

1

13

High-throughput

0.417

High

280991

OST4
Dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit 4

1

0

High-throughput

0.279

Low

281039

TUSC3
Dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit TUSC3

1

0

High-throughput

0.279

Low

139781

RCAS1
Receptor-binding cancer antigen expressed on SiSo cells

1

0

High-throughput

0.249

Low

281040

STIM1
Stromal interaction molecule 1

1

0

High-throughput

0.249

Low

281077

S2546
Mitochondrial outer membrane protein SLC25A46

1

0

High-throughput

0.249

Low

281081

COX14
Cytochrome c oxidase assembly protein COX14

1

0

High-throughput

0.249

Low


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Last updated: 11Aug2025