HitPredict

Interactor 1: HSC82 (P15108)
ATP-dependent molecular chaperone HSC82 (82 kDa heat shock cognate protein) (Heat shock protein Hsp90 constitutive isoform)
Gene: HSC82

Interactor 2: PRP4 (P20053)
U4/U6 small nuclear ribonucleoprotein PRP4 (Pre-mRNA-processing protein 4)
Gene: PRP4

Species: Saccharomyces cerevisiae S288C

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.50	0.437

Property	Details
Experiments	37295430
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	-
Homologous interactions	11

Homologous interactions

Color coding for hit scores

	1 705 Sc			1 465
+	Sc
		365770 HSP82_YEAST (1-705): 0: 968: 95.63		PRP4_YEAST (1-465): 7.32e-119: 357: 100.00
+	Hs
		438057 HS90B_HUMAN (5-705): 0: 1022: 61.15		GBB2_HUMAN (124-465): 6.32e-91: 281: 24.56
+	Hs
		437971 HS90B_HUMAN (5-705): 0: 1022: 61.15		LIS1_HUMAN (214-465): 1.47e-74: 241: 22.96
+	Hs
		431630 HS90A_HUMAN (4-705): 0: 1013: 60.67		LIS1_HUMAN (214-465): 1.47e-74: 241: 22.96
+	Hs
		438048 HS90B_HUMAN (5-705): 0: 1022: 61.15		WDR5_HUMAN (69-334): 3.26e-56: 191: 15.94
+	Hs
		538141 ENPL_HUMAN (3-680): 0: 893: 47.10		LIS1_HUMAN (214-465): 1.47e-74: 241: 22.96
+	Hs
		438620 HS90B_HUMAN (5-705): 0: 1022: 61.15		PRP19_HUMAN (141-465): 1.26e-22: 102: 24.92
+	Hs
		432362 HS90A_HUMAN (4-705): 0: 1013: 60.67		PRP19_HUMAN (141-465): 1.26e-22: 102: 24.92
+	Hs
		538184 ENPL_HUMAN (3-680): 0: 893: 47.10		WDR5_HUMAN (69-334): 3.26e-56: 191: 15.94
+	Sc
		543602 HSC82_YEAST (1-705): 0: 977: 100.00		TAF5_YEAST (261-380): 1.14e-16: 84.7: 33.88
+	Sc
		366167 HSP82_YEAST (1-705): 0: 968: 95.63		TAF5_YEAST (261-380): 1.14e-16: 84.7: 33.88