HitPredict

Interactor 1: HSC82 (P15108)
ATP-dependent molecular chaperone HSC82 (82 kDa heat shock cognate protein) (Heat shock protein Hsp90 constitutive isoform)
Gene: HSC82

Interactor 2: TRX2 (P22803)
Thioredoxin-2 (Thioredoxin II) (TR-II) (Thioredoxin-1)
Gene: TRX2

Species: Saccharomyces cerevisiae S288C

Source: biogrid

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.56	0.60	0.584

Property	Details
Experiments	23414292, 31399574
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005737 - cytoplasm GO:0005829 - cytosol
Homologous interactions	6

Homologous interactions

Color coding for hit scores

	1 705 Sc			1 104
+	Hs
		431462 HS90A_HUMAN (4-705): 0: 1013: 60.67		THIO_HUMAN (1-104): 2.21e-36: 120: 48.57
+	Sc
		543214 HSC82_YEAST (1-705): 0: 977: 100.00		TRX1_YEAST (1-103): 9.82e-38: 124: 78.64
+	Sc
		365815 HSP82_YEAST (1-705): 0: 968: 95.63		TRX2_YEAST (1-104): 5.03e-39: 127: 100.00
+	Sc
		365806 HSP82_YEAST (1-705): 0: 968: 95.63		TRX1_YEAST (1-103): 9.82e-38: 124: 78.64
+	Hs
		538242 ENPL_HUMAN (3-680): 0: 893: 47.10		PDIA6_HUMAN (6-98): 2.01e-29: 110: 22.92
+	Hs
		531703 ENPL_HUMAN (3-680): 0: 893: 47.10		PDIA4_HUMAN (3-103): 9.76e-27: 104: 21.30