HitPredict

Interactor 1: HSC82 (P15108)
ATP-dependent molecular chaperone HSC82 (82 kDa heat shock cognate protein) (Heat shock protein Hsp90 constitutive isoform)
Gene: HSC82

Interactor 2: SPT7 (P35177)
Transcriptional activator SPT7
Gene: SPT7

Species: Saccharomyces cerevisiae S288C

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.47	0.60	0.536

Property	Details
Experiments	21734642
Identification Methods	affinity chromatography technology, tandem affinity purification
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005739 - mitochondrion
Homologous interactions	9

Homologous interactions

Color coding for hit scores

	1 705 Sc			1 1332
+	Sc
		366084 HSP82_YEAST (1-705): 0: 968: 95.63		SPT7_YEAST (1-1332): 0: 1183: 100.00
+	Hs
		438597 HS90B_HUMAN (5-705): 0: 1022: 61.15		BAZ2B_HUMAN (134-547): 2.87e-69: 259: 18.52
+	Hs
		432282 HS90A_HUMAN (4-705): 0: 1013: 60.67		BRD7_HUMAN (341-931): 1.06e-58: 217: 12.89
+	Sc
		544268 HSC82_YEAST (1-705): 0: 977: 100.00		RSC4_YEAST (244-866): 6.47e-49: 187: 13.58
+	Sc
		366757 HSP82_YEAST (1-705): 0: 968: 95.63		RSC4_YEAST (244-866): 6.47e-49: 187: 13.58
+	Hs
		538160 ENPL_HUMAN (3-680): 0: 893: 47.10		SMCA4_HUMAN (199-590): 5.78e-62: 235: 11.04
+	Rn
		948938 HS90A_RAT (4-705): 0: 1014: 60.59		Q6AYL3_RAT (288-492): 1.41e-13: 75.4: 12.80
+	Sc
		544312 HSC82_YEAST (1-705): 0: 977: 100.00		GCN5_YEAST (435-548): 5.76e-20: 96.4: 29.83
+	Sc
		366797 HSP82_YEAST (1-705): 0: 968: 95.63		GCN5_YEAST (435-548): 5.76e-20: 96.4: 29.83