Protein: NCOA4
Nuclear receptor coactivator 4 (NCoA-4) (Androgen receptor coactivator 70 kDa protein) (70 kDa AR-activator) (70 kDa androgen receptor coactivator) (Androgen receptor-associated protein of 70 kDa) (Ferritin cargo receptor NCOA4) (Ret-activating protein ELE1)

Gene: NCOA4
Organism: Homo sapiens
Interactions: 62
UniProt ID: Q13772

Gene Ontology (top 5):
GO:0003713 - transcription coactivator activity
GO:0005634 - nucleus
GO:0005654 - nucleoplasm
GO:0005694 - chromosome
GO:0005776 - autophagosome

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

520025

ANDR
Androgen receptor

13

3

Small-scale

0.763

High

391613

FRIH
Ferritin heavy chain

7

2

Small-scale

0.750

High

342863

HERC2
E3 ubiquitin-protein ligase HERC2

6

2

Small-scale

0.737

High

391249

FRIL
Ferritin light chain

4

2

Small-scale

0.699

High

1117265

TRIM1
Probable E3 ubiquitin-protein ligase MID2

2

1

High-throughput

0.606

High

789492

PPARG
Peroxisome proliferator-activated receptor gamma

2

4

Small-scale

0.594

High

1117243

TAXB1
Tax1-binding protein 1

2

1

Small-scale

0.584

High

1117258

TRIM7
E3 ubiquitin-protein ligase TRIM7

1

1

Small-scale

0.561

High

543505

VDR
Vitamin D3 receptor

1

3

Small-scale

0.527

High

625812

RXRA
Retinoic acid receptor RXR-alpha

1

1

Small-scale

0.527

High

138101

PSDE
26S proteasome non-ATPase regulatory subunit 14

1

0

High-throughput

0.513

High

968698

PRS4
26S proteasome regulatory subunit 4

1

0

High-throughput

0.513

High

1117234

MK06
Mitogen-activated protein kinase 6

1

0

High-throughput

0.513

High

1117240

UBP43
Ubiquitin carboxyl-terminal hydrolase 43

1

0

High-throughput

0.513

High

1117245

RNF10
E3 ubiquitin-protein ligase RNF10

1

0

High-throughput

0.513

High

1117253

GMCL1
Germ cell-less protein-like 1

1

0

High-throughput

0.513

High

396074

ESR1
Estrogen receptor

1

4

Small-scale

0.501

High

1117255

ATX2
Ataxin-2

1

1

High-throughput

0.494

High

728224

AKT1
RAC-alpha serine/threonine-protein kinase

1

0

High-throughput

0.486

High

404045

GCR
Glucocorticoid receptor

1

3

Small-scale

0.481

High

1025095

TF2B
Transcription initiation factor IIB

1

0

Small-scale

0.480

High

1117251

KAT2B
Histone acetyltransferase KAT2B

1

0

Small-scale

0.480

High

219954

XRCC3
DNA repair protein XRCC3

1

1

High-throughput

0.479

High

778066

VGFR2
Vascular endothelial growth factor receptor 2

1

1

High-throughput

0.479

High

1095620

CACO2
Calcium-binding and coiled-coil domain-containing protein 2

1

1

High-throughput

0.479

High

1107698

SQSTM
Sequestosome-1

1

2

High-throughput

0.479

High

1117242

HUWE1
E3 ubiquitin-protein ligase HUWE1

1

1

High-throughput

0.479

High

1117259

TRIM5
Tripartite motif-containing protein 5

1

1

Small-scale

0.479

High

1117249

JPH3
Junctophilin-3

1

1

High-throughput

0.470

High

1117264

ATX10
Ataxin-10

1

1

High-throughput

0.470

High

172795

XPO1
Exportin-1

1

0

High-throughput

0.458

High

400806

RAF1
RAF proto-oncogene serine/threonine-protein kinase

1

0

High-throughput

0.458

High

629849

BTF3
Transcription factor BTF3

1

0

High-throughput

0.458

High

1113056

CUL3
Cullin-3

1

0

High-throughput

0.458

High

1117233

NBR1
Next to BRCA1 gene 1 protein

1

0

High-throughput

0.458

High

1117239

BAKOR
Beclin 1-associated autophagy-related key regulator

1

0

High-throughput

0.458

High

1117252

OPTN
Optineurin

1

0

High-throughput

0.458

High

1117260

MLP3B
Microtubule-associated protein 1 light chain 3 beta

1

0

High-throughput

0.458

High

1117261

EGLN3
Prolyl hydroxylase EGLN3

1

0

High-throughput

0.458

High

838493

GRIA2
Glutamate receptor 2

1

1

High-throughput

0.437

High

1117241

KI21A
Kinesin-like protein KIF21A

1

1

High-throughput

0.437

High

1117250

TFG
Protein TFG

1

1

High-throughput

0.437

High

1117256

KIFC3
Kinesin-like protein KIFC3

1

1

High-throughput

0.437

High

1117237

A16L1
Autophagy-related protein 16-1

1

0

High-throughput

0.426

High

1117262

HIF1N
Hypoxia-inducible factor 1-alpha inhibitor

1

0

High-throughput

0.426

High

1117246

PRLD2
PRELI domain-containing protein 2

1

0

High-throughput

0.279

Low

1117254

NEUL4
Neuralized-like protein 4

1

0

High-throughput

0.279

Low

58816

PIPSL
Putative PIP5K1A and PSMD4-like protein

1

0

High-throughput

0.232

Low

133251

P2Y10
Putative P2Y purinoceptor 10

1

0

High-throughput

0.232

Low

567856

PRG2
Bone marrow proteoglycan

1

0

High-throughput

0.232

Low

638412

FPR1
fMet-Leu-Phe receptor

1

0

High-throughput

0.232

Low

880138

PTH2R
Parathyroid hormone 2 receptor

1

0

High-throughput

0.232

Low

993891

TYB10
Thymosin beta-10

1

0

Small-scale

0.232

Low

1117235

DOXA2
Dual oxidase maturation factor 2

1

0

High-throughput

0.232

Low

1117236

CF141
Uncharacterized protein C6orf141

1

0

High-throughput

0.232

Low

1117238

ZNT6
Zinc transporter 6

1

0

High-throughput

0.232

Low

1117244

LYPD1
Ly6/PLAUR domain-containing protein 1

1

0

High-throughput

0.232

Low

1117247

GTR12
Solute carrier family 2, facilitated glucose transporter member 12

1

0

High-throughput

0.232

Low

1117248

NET5
Netrin-5

1

0

High-throughput

0.232

Low

1117257

S17A9
Voltage-gated purine nucleotide uniporter SLC17A9

1

0

High-throughput

0.232

Low

1117263

WRP73
WD repeat-containing protein WRAP73

1

0

High-throughput

0.232

Low

1117266

ASB4
Ankyrin repeat and SOCS box protein 4

1

0

High-throughput

0.232

Low


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Last updated: 11Aug2025