HitPredict

Interactor 1: HSC82 (P15108)
ATP-dependent molecular chaperone HSC82 (82 kDa heat shock cognate protein) (Heat shock protein Hsp90 constitutive isoform)
Gene: HSC82

Interactor 2: ARB1 (P40024)
ABC transporter ATP-binding protein ARB1 (EC 3.6.5.-) (ATP-binding cassette protein involved in ribosome biogenesis 1)
Gene: ARB1

Species: Saccharomyces cerevisiae S288C

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.60	0.479

Property	Details
Experiments	31399574
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005524 - ATP binding GO:0005737 - cytoplasm GO:0016887 - ATP hydrolysis activity
Homologous interactions	9

Homologous interactions

Color coding for hit scores

	1 705 Sc			1 610
+	Sc
		366351 HSP82_YEAST (1-705): 0: 968: 95.63		ARB1_YEAST (1-610): 4.01e-167: 491: 100.00
+	Sc
		543939 HSC82_YEAST (1-705): 0: 977: 100.00		GCN20_YEAST (14-607): 1.34e-123: 384: 34.57
+	Sc
		366472 HSP82_YEAST (1-705): 0: 968: 95.63		GCN20_YEAST (14-607): 1.34e-123: 384: 34.57
+	Sc
		544552 HSC82_YEAST (1-705): 0: 977: 100.00		NEW1_YEAST (85-500): 2.74e-38: 153: 28.27
+	Sc
		367040 HSP82_YEAST (1-705): 0: 968: 95.63		NEW1_YEAST (85-500): 2.74e-38: 153: 28.27
+	Sc
		543127 HSC82_YEAST (1-705): 0: 977: 100.00		EF3A_YEAST (203-307): 5.93e-14: 77.3: 24.53
+	Sc
		544218 HSC82_YEAST (1-705): 0: 977: 100.00		EF3B_YEAST (203-307): 6.74e-14: 77.3: 25.47
+	Sc
		365733 HSP82_YEAST (1-705): 0: 968: 95.63		EF3A_YEAST (203-307): 5.93e-14: 77.3: 24.53
+	Ca
		639865 HSP90_CANAL (4-705): 0: 953: 82.36		EF3_CANAL (165-307): 8.02e-13: 73.8: 20.83